过氧化还原酶5/6抗体

参考价:¥1
供货周期: 现货
品牌: GenWay
规格: 0.1ml/100μg和0.2ml/200μg等规格
货号:
CAS号:
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英文名称  Anti-PRDX5/PRDX6

中文名称  过氧化还原酶5/6抗体

别    名  1 Cys; 1 Cys peroxiredoxin; 1 Cys PRX; 1 cysPrx; 24 kDa protein; Acidic calcium independent phospholipase A2; aiPLA2; Antioxidant protein 2; AOP2; Aop2 rs3; Brp 12; Ciliary body glutathione peroxidase; CP 3; GPx; Liver 2D page spot 40; Ltw4; Lvtw 4; Non selenium glutathione peroxidase; NSGPx; ORF06; p29; Peroxiredoxin6; Peroxiredoxin 6; Peroxiredoxin-6; Peroxiredoxin5; Peroxiredoxin 5; Peroxiredoxin-5; PHGPx; Phospholipase A2 lysosomal; PLA2; PRDX 6; Prdx5; PRDX6; PRX; Red blood cells page spot 12; Thiol specific antioxidant protein; AA690119; Prdx6 rs3.

浓    度  1mg/1ml

规 格  0.1ml/100μg  0.2ml/200μg

抗体来源  Rabbit  

克隆类型  polyclonal

交叉反应  Human, Mouse, Rat, Dog, Pig, Cow, Horse

产品类型  一抗    

研究领域  肿瘤 细胞生物 免疫学 细胞凋亡 干扰素  

蛋白分子量  predicted molecular weight: 18/25kDa

性    状  Lyophilized or Liquid

过氧化还原酶5/6抗体的功能抗体的主要功能是与抗原(包括外来的和自身的)相结合,从而有效地清除侵入机体内的微生物、寄生虫等异物,抗体(antibody)是一种应答抗原产生的、可与抗原特异性结合的蛋白质。每种抗体与特定的抗原决定基结合。这种结合可以使抗原失活,也可能无效但有时也会对机体造成病理性损害,如抗核抗体、抗双链DNA抗体、抗甲状腺球蛋白抗体等一些自身抗体的产生,对人体可造成危害。

免 疫 原  KLH conjugated synthetic peptide derived from human Peroxiredoxin 6 (55-100aa)

亚    型  IgG

纯化方法  affinity purified by Protein A

储 存 液  0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500

(石蜡切片需做抗原修复)

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 Peroxiredoxin (Prx) is in the peroxidase family, whose mammalian members have been known to contribute to cell proliferation, differentiation and apoptosis. Many isoforms (about 50 proteins), collected in accordance with amino acid sequence homology, particularly the amino terminal region containing active site cysteine residue, and the thiol specific antioxidant activity, distribute throughout all the kingdoms. Mammalian Prx consists of 6 different members grouped into typical 2 Cys, atypical 2 Cys Prx, and 1 Cys Prx. Except PrxVI belonging to the 1 Cys Prx subgroup, the other five 2 Cys Prx isotypes have the thioredoxin dependent peroxidase(TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20–30 kDa in molecular size and vary in subcellularlocalization: PrxI, II, and VI in cytosol; PrxIII in mitochondria; PrxIV in ER and secretion; PrxV shows complicated distribution including peroxisome, mitochondria and cytosol.

Subunit : Monomer.

过氧化还原酶5/6抗体Subcellular Location : Mitochondrion. Cytoplasm. Peroxisome.

Tissue Specificity : Widely expressed.

Similarity : Belongs to the peroxiredoxin 2 family.

Contains 1 thioredoxin domain.


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