MAWD结合蛋白抗体

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英文名称  Anti-PBLD

中文名称  MAWD结合蛋白抗体

别    名  MAWBP; MAWD binding protein; MAWD-binding protein; MAWDBP; PBLD; PBLD_HUMAN; Phenazine biosynthesis like domain containing protein; Phenazine biosynthesis like protein domain containing; Phenazine biosynthesis-like domain-containing protein; Unknown protein 32 from 2D page of liver tissue; Unknown protein 32 from 2D-page of liver tissue; FLJ14767; FLJ35507; OTTHUMP00000019698; OTTHUMP00000082489.

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit  

克隆类型  polyclonal

交叉反应  Human, Mouse, Rat, Cow, Horse

产品类型  一抗    

研究领域  细胞生物 免疫学  

蛋白分子量  predicted molecular weight: 32kDa

性    状  Lyophilized or Liquid

MAWD结合蛋白抗体的功能抗体的主要功能是与抗原（包括外来的和自身的）相结合，从而有效地清除侵入机体内的微生物、寄生虫等异物，抗体（antibody）是一种应答抗原产生的、可与抗原特异性结合的蛋白质。每种抗体与特定的抗原决定基结合。这种结合可以使抗原失活，也可能无效但有时也会对机体造成病理性损害，如抗核抗体、抗双链DNA抗体、抗甲状腺球蛋白抗体等一些自身抗体的产生，对人体可造成危害。

免 疫 原  KLH conjugated synthetic peptide derived from human PBLD/MAWBP

亚    型  IgG

纯化方法  affinity purified by Protein A

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:50-200

（石蜡切片需做抗原修复）

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 MAWDBP (MAWD binding protein), also known as PBLD (phenazine biosynthesis-like protein domain containing) or MAWBP, is a 288 amino acid protein that belongs to the phenazine biosynthesis-like protein (PhzF) family. It has been suggested that MAWDBP is the only representative of the PhzF family in the human genome. Expressed in most tissues, MAWDBP is a WD-40 repeat-containing β-propeller protein believed to participate in the MAPK signaling pathway. Involved in multiple basic cellular functions, expression of MAWDBP is elevated in several disease processes, including insulin resistance, folate deficiency and hypotension. It is thought that MAWDBP may also be involved in carcinogenesis.

Subunit : Interacts with UNRIP/MAWD.

Similarity : Belongs to the phzF family.

Database links :

MAWD结合蛋白抗体Entrez Gene: 64081 Human

Omim: 612189 Human

SwissProt: P30039 Human

Unigene: 198158 Human