原钙粘蛋白β11抗体

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英文名称  Anti-PCDHB11

中文名称  原钙粘蛋白β11抗体

别    名  MGC138337; Cadherin ME2; ME2; MGC138337; MGC142171; MGC142171; PCDBB_HUMAN; PCDH beta 11; PCDH BETA11; PCDH-beta-11; PCDHB11; Protocadherin beta 11; Protocadherin beta-11.

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit  

克隆类型  polyclonal

交叉反应  Human, Mouse, Rat, Pig, Cow, Horse, Rabbit

产品类型  一抗    

研究领域  肿瘤 细胞生物 免疫学 神经生物学 信号转导 细胞粘附分子 细胞骨架 细胞膜蛋白  

蛋白分子量  predicted molecular weight: 84kDa

性    状  Lyophilized or Liquid

原钙粘蛋白β11抗体随着国内抗体行业的崛起，我国自主品牌的抗体，都蛮多了，质量也不错，技术在逐渐成熟，价格也比国外的廉价的多，受到国内顾客的热捧，我们公司为了方便客户，特推出阴离子转运蛋白-1抗体规格15ug、30ug、50ug、100ug，15ug和30ug等，我们全国包邮，大中城市免费快递。抗体分子是生物学和医学领域用途最为广泛的蛋白分子。抗体作为疾病预防、诊断和治疗的制剂已有上百年的发展历史。随着生命科学研究的迅猛发展，抗体工程在生物技术领域越来越占有非常重要的地位。我公司可为您提供快速的、高质量的和经济的多克隆抗体制备服务，并将成为您在科研及生产中的得力助手。

免 疫 原  KLH conjugated synthetic peptide derived from human PCDHB11

亚    型  IgG

纯化方法  affinity purified by Protein A

储 存 液  0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  IF=1:100-500

（石蜡切片需做抗原修复）

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 PCDHB11 is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. PCDHB11 clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

Function : Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

原钙粘蛋白β11抗体Subcellular Location : Cell membrane; Single-pass type I membrane protein (By similarity).

Similarity : Contains 6 cadherin domains.

Database links : UniProtKB/Swiss-Prot: Q9Y5F2.1