CTSK Antibody

2015-03-24 10:33 下载量：0

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产品名称： CTSK Antibody 别称： CTS02; CTSO; CTSO1; CTSO2; MGC23107; PKND; PYCD; 货号： EAP0618 来源：兔亚型： IgG 纯化方法：抗原亲和纯化性状：溶液浓度： 1mg/mL 组分： PBS，0.02% 叠氮钠，50% 甘油， pH7.3 储存条件：短期使用可保存于-20°C。长期使用可分装后保存于-80°C。避免反复冻融。应用用途： WB IHC 反应性： H M R 推荐稀释比： WB(1: 500-1: 2000); IHC(1: 50-1: 200); IF(1: 50-1: 200) 免疫原信息名称： Recombinant protein of human CTSK 预估 MW：实测 MW： 39kDa 图片 Western blot analysis of extracts of mouse uterus tissue cell line, using CTSK antibody. www.elabscience.com ELABSCIENCE BIOTECHNOLOGY CO.,LTD FOR RESEARCH USE ONLY Elabscience www.elabscience.cn 背景知识 CTSK(cathepsin K), also named as CTSO, CTSO2, is a recently identified lysosomal cysteine proteinase. CTSK is synthesized as a proenzyme of 38 kDa and subsequently enters acidic lysosomal compartments, in which the propeptide is cleaved and transformed into an active enzyme and it may influence adipocyte differentiation through modifying extracellular matrix components(PMID:16912123). It is revealed both the 46-kDa cathepsin-K precursor and the 30-kDa mature form in mouse bone extracts(PMID:9811821). The high CTSK protein levels are only detected in primary cultured fibroblasts derived from normal and neoplastic breast tissue, where the 37- and 25-kDa bands to be detected correspond to pro- and mature proteins through western blot(PMID:18765527). The full length protein has a signal peptides with 15 amino acids and a propeptide with 99 amino acids. This antibody is specific to CTSK.

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上海万疆生物技术有限公司

铜牌会员 | 第2年

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