供货周期: | 一周 |
品牌: | EterLife |
规格: | 0.1ml/100μg /0.2ml/200μg |
货号: | TE-KT-0084 |
CAS号: | 详见产品说明书 |
ATP5E蛋白抗体
〖别名〗ATP 5E; ATP synthase epsilon chain mitochondrial; ATP synthase H+ transporting mitochondrial F1 complex epsilon subunit; ATP synthase subunit epsilon; ATP5E; ATP5E_HUMAN; ATPase subunit epsilon; ATPE; F(0)F(1) ATPase; H(+) transporting two sector ATPase; MGC104243; mitochondrial; Mitochondrial ATP synthase epsilon chain; Mitochondrial ATPase.
〖浓度〗1mg/1ml
〖规格〗0.2ml/200μg
〖抗体来源〗ATP5E蛋白抗体Rabbit
〖克隆类型〗polyclonal
〖交叉反应〗Human, Pig,
〖产品类型〗一抗
〖研究领域〗肿瘤 细胞生物 新陈代谢 表观遗传学
〖蛋白分子量〗predicted molecular weight: 6kDa
〖性状〗Lyophilized or Liquid
〖免疫原〗KLH conjugated synthetic peptide derived from human ATP5E
〖亚型〗IgG
〖纯化方法〗affinity purified by Protein A
〖储存液〗Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
〖产品应用〗ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
〖保存条件〗Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
〖产品介绍〗Mitochondrial ATP synthases (ATPases) transduce the energy contained in membrane electrochemical proton gradients into the energy required for synthesis of high-energy phosphate bonds. ATPases contain two linked complexes: F1, the hydrophilic catalytic core; and F0, the membrane-embedded protein channel. F1 consists of three Alpha chains and three Beta chains, which are weakly homologous, as well as one Gamma chain, one Delta chain and one e chain. F0 consists of three subunits: a, b and c. The e chain of F1 contains 50 amino acids and is the smallest of the five ATPase F1 chains. Mitochondrial ATPase e chain (ATP5E) localizes to the mitochondria and catalyzes ATP synthesis.
Function : Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
Subunit : F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) seems to have nine subunits: a, b, c, d, e, f, g, F6 and 8 (or A6L). Component of an ATP synthase complex composed of ATP5F1, ATP5G1, ATP5E, ATP5H, ATP5I, ATP5J, ATP5J2, MT-ATP6, MT-ATP8, ATP5A1, ATP5B, ATP5D, ATP5C1, ATP5O, ATP5L, USMG5 and MP68 (By similarity).
Subcellular Location : Mitochondrion. Mitochondrion inner membrane.
Tissue Specificity : Ubiquitous.
DISEASE : Defects in ATP5E are the cause of mitochondrial complex V deficiency nuclear type 3 (MC5DN3) [MIM:614053]. MC5DN3 is a mitochondrial disorder with heterogeneous clinical manifestations including dysmorphic features, psychomotor retardation, hypotonia, growth retardation, cardiomyopathy, enlarged liver, hypoplastic kidneys and elevated lactate levels in urine, plasma and cerebrospinal fluid.
Similarity : Belongs to the eukaryotic ATPase epsilon family.
Database links : UniProtKB/Swiss-Prot: P56381.2
本公司产品现货供应,货期短,质量可靠。仅用于科研实验不应用于临床。我们用专业的态度,一流的服务,全程实验指导,让你的数据不在成为实验奇谈。选择优质的ATP5E蛋白抗体,你的小伙伴都会惊呆的。本公司专业供应各种进口、国产一抗及二抗。代理品牌有R&D、Santa Cruz、Bipec、Millipore等国际知名品牌,品种多达7000多种。让你的科研之路不再布满荆棘。
我们还可以为客户提供产品说明书。ATP5E蛋白抗体拥有高纯度、高效价、高特异性的特点,可以应用于多种实验。免费送货上门,为您大大节省了时间和金钱。
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Ab-(001)-04284 Anti-YY1 核转录因子YY1抗体 ,英文名: Anti-YY1 ,规格: 0.2ml
Ab-(001)-04285 Anti-XAF1 XIAP相关因子1凋亡抑制蛋白抗体 ,英文名: Anti-XAF1 ,规格: 0.1ml
Ab-(001)-04286 Anti-XRCC1 X射线修复交叉互补蛋白抗体 ,英文名: Anti-XRCC1 ,规格: 0.2ml
Ab-(001)-04287 Anti-XBP-1 细胞核转录因子X盒结合蛋白抗体 ,英文名: Anti-XBP-1 ,规格: 0.2ml
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Ab-(001)-04298 Anti-ZNF307 锌指蛋白307抗体 ,英文名: Anti-ZNF307 ,规格: 0.2ml
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Ab-(001)-04302 Anti-Zyxin/ESP 2 斑联蛋白抗体 ,英文名: Anti-Zyxin/ESP ,规格: 0.2ml
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Ab-(001)-04304 Anti-人T淋巴细胞亚群检测盒 人T淋巴细胞亚群检测盒 (T-Subset) ,英文名: Anti-人T淋巴细胞亚群检测盒 ,规格: 100人份
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Ab-(001)-04318 Anti-Phospho-beta-Arrestin 1(Ser412) /FITC 荧光素标记磷酸化β抑制蛋白1抗体IgG ,英文名: Anti-Phospho-beta-Arrestin ,规格: 0.2ml
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