供货周期: | 一周 |
品牌: | EterLife |
规格: | 0.1ml/100μg /0.2ml/200μg |
货号: | TE-KT-0087 |
CAS号: | 详见产品说明书 |
ATP6V1B2蛋白抗体
〖别名〗ATP6B1B2; ATP6B2; ATP6V1 B2; ATP6V1B 2; ATP6V1B2; ATPase H+ transporting lysosomal 56/58kDa V1 subunit B isoform 2; ATPase H+ transporting lysosomal 56/58kDa V1 subunit B2; ATPase H+ transporting, lysosomal (vacuolar proton pump) beta polypeptide 56/58kD isoform 2; ATPase, H+ transporting, lysosomal V1 subunit B2; brain isoform; Endomembrane proton pump 58 kDa subunit; H+ transporting two sector ATPase; HO 57; HO57; V ATPase B2 subunit; V ATPase subunit B 2; V type proton ATPase subunit B, brain isoform; V-ATPase subunit B 2; V-type proton ATPase subunit B; Vacuolar ATP synthase subunit B brain isoform; Vacuolar H+ ATPase 56,000 subunit; Vacuolar H+ ATPase 56000 subunit; Vacuolar H+ATPase B2; Vacuolar proton pump subunit B 2; VAT B2; VATB 2; VATB; VATB2; VATB2_HUMAN; Vma 2; Vma2; VPP 3; VPP3.
〖浓度〗1mg/1ml
〖规格〗ATP6V1B2蛋白抗体0.2ml/200μg
〖抗体来源〗Rabbit
〖克隆类型〗polyclonal
〖交叉反应〗Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Cynomolgus Monkey, Orangutan
〖产品类型〗一抗
〖研究领域〗肿瘤 细胞生物 免疫学 神经生物学 信号转导 新陈代谢 表观遗传学
〖蛋白分子量〗predicted molecular weight: 56kDa
〖性状〗Lyophilized or Liquid
〖免疫原〗KLH conjugated synthetic peptide derived from human ATP6V1B2/V-ATPase B2
〖亚型〗IgG
〖纯化方法〗affinity purified by Protein A
〖储存液〗Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
〖产品应用〗WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
〖保存条件〗Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
〖产品介绍〗Vacuolar-type H+-ATPase (V-ATPase) is a multisubunit enzyme responsible for acidification of eukaryotic intracellular organelles. V-ATPases pump protons against an electrochemical gradient, while F-ATPases reverse the process, thereby synthesizing ATP. A peripheral V1 domain, which is responsible for ATP hydrolysis, and a integral V0 domain, which is responsible for proton translocation, compose V-ATPase. Nine subunits (A–H) make up the V1 domain and five subunits (a, d, c, c' and c") make up the V0 domain. Like F-ATPase, V-ATPase most likely operates through a rotary mechanism. The V-ATPase V1 B subunit exists as two isoforms. In the inner ear, the V-ATPase B1 isoform functions in proton secretion and is required to maintain proper endolymph pH and normal auditory function. The gene encoding the human V-ATPase B1 isoform maps to chromosome 2cen-q13. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness. The V-ATPase B2 isoform is expressed in kidney and is the only B isoform expressed in osteoclasts. The gene encoding the human V-ATPase B2 isoform maps to chromosome 8p22-p21.
Function : Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Subunit : V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (main components: subunits A, B, C, D, E, and F) attached to an integral membrane V0 proton pore complex (main component: the proteolipid protein).
Subcellular Location : Endomembrane system. Melanosome. Endomembrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Similarity : Belongs to the ATPase alpha/beta chains family.
Database links : UniProtKB/Swiss-Prot: P21281.3
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我们还可以为客户提供产品说明书。ATP6V1B2蛋白抗体拥有高纯度、高效价、高特异性的特点,可以应用于多种实验。免费送货上门,为您大大节省了时间和金钱。
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Ab-(001)-04468 Anti-ANGPTL4/ANG-4 /FITC 荧光素标记血管位蛋白样4/血管生成素样蛋白-4抗体IgG ,英文名: Anti-ANGPTL4/ANG-4 ,规格: 0.2ml
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Ab-(001)-04471 Anti-Annexin III /FITC 荧光素标记膜粘连蛋白 Ⅲ抗体IgG ,英文名: Anti-Annexin ,规格: 0.2ml
Ab-(001)-04472 Anti-Annexin IV /FITC 荧光素标记膜粘连蛋白 Ⅳ抗体IgG ,英文名: Anti-Annexin ,规格: 0.2ml
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