供货周期: | 一周 |
品牌: | EterLife |
规格: | 0.1ml/100μg 、0.2ml/200μg |
货号: | TE-KT-0090 |
CAS号: | 详见产品说明书 |
磷酸化有丝分裂激酶B抗体
〖别名〗Aurora B (phospho Y12); Aurora B (phospho T12); AIK2; AIM1; ARK2; AurB; AURKB; Aurora 1; Aurora and Ipl1 like midbody associated protein 1; Aurora kinase B; Aurora related kinase 2; Aurora-B; Aurora/IPL1 related kinase 2; IPL1; Serine/theronine kinase 12; Serine/threonine protein kinase 12; STK1; STK12; STK5.
〖浓度〗1mg/1ml
〖规格〗磷酸化有丝分裂激酶B抗体0.1ml/100μg
〖抗体来源〗Rabbit
〖克隆类型〗polyclonal
〖交叉反应〗Human, Mouse, Rat
〖产品类型〗一抗 磷酸化抗体
〖研究领域〗肿瘤 细胞生物 神经生物学 信号转导 激酶和磷酸酶
〖蛋白分子量〗predicted molecular weight: 39kDa
〖性状〗Lyophilized or Liquid
〖免疫原〗KLH conjugated Synthesised phosphopeptide derived from human Aurora B around the phosphorylation site of Tyr12
〖亚型〗IgG
〖纯化方法〗affinity purified by Protein A
〖储存液〗Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
〖产品应用〗WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
〖保存条件〗Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
〖产品介绍〗Mahogany (MG), originally identified as a protein involved in pigmentation, acts in conjunction with melanocortin receptors to suppress diet-induced obesity. Mahogany contains a single transmembrane domain, and it is expressed in a broad range of tissues, including the hypothalamus and pigment cells. Mutations within the mahogany gene were shown to rescue agouti-lethal-yellow mutant mice from obesity. The extracellular domain of mouse mahogany is the ortholog of the human protein attractin. Attractin (also designated DPPT-L) is a human serum glycoprotein and is a member of the CUB family of cell adhesion and guidance proteins. Attractin is expressed on activated T cells and is released from the cells 48 to 72 hours after activation.
Function : May be directly involved in regulating the cleavage of polar spindle microtubules and is a key regulator for the onset of cytokinesis during mitosis. Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Phosphorylates 'Ser-10' and 'Ser-28' of histone H3 during mitosis. Required for kinetochore localization of BUB1 and SGOL1. Interacts with INCENP.
Subcellular Location : Nucleus. Chromosome. Chromosome > centromere. Cytoplasm > cytoskeleton > spindle. Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis. Colocalized with gamma tubulin in the mid-body.
Tissue Specificity : High level expression seen in the thymus. It is also expressed in the spleen, lung, testis, colon, placenta and fetal liver. Expressed during S and G2/M phase and expression is up-regulated in cancer cells during M phase.
Post-translational modifications : Ubiquitinated by different BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complexes. Ubiquitinated by the BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex, ubiquitination leads to removal from mitotic chromosomes and is required for cytokinesis. During anaphase, the BCR(KLHL21) E3 ubiquitin ligase complex recruits the CPC complex from chromosomes to the spindle midzone and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
DISEASE : Note=Disruptive regulation of expression is a possibile mechanism of the perturbation of chromosomal integrity in cancer cells through its dominant-negative effect on cytokinesis.
Similarity : Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
Contains 1 protein kinase domain.
本公司产品现货供应,货期短,质量可靠。仅用于科研实验不应用于临床。我们用专业的态度,一流的服务,全程实验指导,让你的数据不在成为实验奇谈。选择优质的磷酸化有丝分裂激酶B抗体,你的小伙伴都会惊呆的。本公司专业供应各种进口、国产一抗及二抗。代理品牌有R&D、Santa Cruz、Bipec、Millipore等国际知名品牌,品种多达7000多种。让你的科研之路不再布满荆棘。
我们还可以为客户提供产品说明书。磷酸化有丝分裂激酶B抗体拥有高纯度、高效价、高特异性的特点,可以应用于多种实验。免费送货上门,为您大大节省了时间和金钱。
Ab-(001)-04580 Anti-B7-H1/PDL1/CD274 /FITC 荧光素标记程序性死亡配体1抗体IgG ,英文名: Anti-B7-H1/PDL1/CD274 ,规格: 0.2ml
Ab-(001)-04581 Anti-B7-H4/FITC 荧光素标记B7H4抗体IgG ,英文名: Anti-B7-H4/FITC ,规格: 0.2ml
Ab-(001)-04582 Anti-BACE/ASP2 /FITC 荧光素标记β分泌酶抗体IgG ,英文名: Anti-BACE/ASP2 ,规格: 0.2ml
Ab-(001)-04583 Anti-Bad/FITC 荧光素标记相关死亡促进因子Bad抗体IgG ,英文名: Anti-Bad/FITC ,规格: 0.2ml
Ab-(001)-04584 Anti-Bad/FITC 荧光素标记相关死亡促进因子Bad抗体IgG ,英文名: Anti-Bad/FITC ,规格: 0.2ml
Ab-(001)-04585 Anti-Phospho-Bad(Ser112) /FITC 荧光素标记兔抗人、大、小鼠磷酸化相关死亡促进因子抗体IgG ,英文名: Anti-Phospho-Bad ,规格: 0.2ml
Ab-(001)-04586 Anti-p-BAD/FITC 荧光素标记抗磷酸化相关死亡促进因子p-BAD抗体IgG ,英文名: Anti-p-BAD/FITC ,规格: 0.2ml
Ab-(001)-04587 Anti-BAD(phospho Ser75,Ser99,Ser118) /FITC 荧光素标记磷酸化相关死亡促进因子抗体IgG ,英文名: Anti-BAD ,规格: 0.2ml
Ab-(001)-04588 Anti-Phospho-Bad(Ser136) /FITC 荧光素标记兔抗人、大、小鼠磷酸化相关死亡促进因子抗体IgG ,英文名: Anti-Phospho-Bad ,规格: 0.2ml
Ab-(001)-04589 Anti-Phospho-Bad(Ser155) /FITC 荧光素标记兔抗人、大、小鼠磷酸化相关死亡促进因子抗体IgG ,英文名: Anti-Phospho-Bad ,规格: 0.2ml
Ab-(001)-04590 Anti-BADH2/FITC 荧光素标记BADH2抗体IgG ,英文名: Anti-BADH2/FITC ,规格: 0.2ml
Ab-(001)-04591 Anti-BAFF/CD257/FITC 荧光素标记TNF家族B细胞激活因子抗体IgG ,英文名: Anti-BAFF/CD257/FITC ,规格: 0.2ml
Ab-(001)-04592 Anti-BAFFR/Tnfrsf13c/CD268/FITC 荧光素标记B细胞活化因子受体抗体IgG ,英文名: Anti-BAFFR/Tnfrsf13c/CD268/FITC ,规格: 0.2ml
Ab-(001)-04593 Anti-Bak/FITC 荧光素标记Bcl-2同源拮抗剂Bak抗体IgG ,英文名: Anti-Bak/FITC ,规格: 0.2ml
Ab-(001)-04594 Anti-Bassoon/BSN /FITC 荧光素标记锌指蛋白231抗体IgG ,英文名: Anti-Bassoon/BSN ,规格: 0.2ml
Ab-(001)-04595 Anti-Batroxobin/FITC 荧光素标记蛇***毒***巴***曲***酶***抗***体IgG ,英文名: Anti-Batroxobin/FITC ,规格: 0.2ml
Ab-(001)-04596 Anti-Bax protein/FITC 荧光素标记 Bax 蛋白抗体IgG ,英文名: Anti-Bax ,规格: 0.2ml
Ab-(001)-04597 Anti-Bax/FITC 荧光素标记Bax抗体IgG ,英文名: Anti-Bax/FITC ,规格: 0.2ml
Ab-(001)-04598 Anti-Bax(phospho Ser184) /FITC 荧光素标记兔抗人、大、小鼠等磷酸化Bax抗体IgG ,英文名: Anti-Bax ,规格: 0.2ml
Ab-(001)-04599 Anti-BBC3/PUMA /FITC 荧光素标记p53正向细胞凋亡调控因子抗体IgG ,英文名: Anti-BBC3/PUMA ,规格: 0.2ml
Ab-(001)-04600 Anti-BCHE/FITC 荧光素标记丁酰胆碱脂酶抗体(N端)IgG ,英文名: Anti-BCHE/FITC ,规格: 0.2ml
Ab-(001)-04601 Anti-BCHE/FITC 荧光素标记丁酰胆碱脂酶抗体(C端)IgG ,英文名: Anti-BCHE/FITC ,规格: 0.2ml
Ab-(001)-04602 Anti-Bcl-2 protein/FITC 荧光素标记 Bcl-2 蛋白抗体IgG ,英文名: Anti-Bcl-2 ,规格: 0.2ml
Ab-(001)-04603 Anti-Bcl-xL/FITC 荧光素标记抗Bcl-xL蛋白抗体IgG ,英文名: Anti-Bcl-xL/FITC ,规格: 0.2ml
Ab-(001)-04604 Anti-p-Bcl-xL(phospho-Ser62)/FITC 荧光素标记抗磷酸化(Ser62)Bcl-xL蛋白抗体IgG ,英文名: Anti-p-Bcl-xL ,规格: 0.2ml
Ab-(001)-04605 Anti-Phospho-Bcl-2 (p-Thr56) /FITC 荧光素标记兔抗人、大、小鼠磷酸化Bcl-2抗体IgG ,英文名: Anti-Phospho-Bcl-2 ,规格: 0.2ml
Ab-(001)-04606 Anti-Phospho-Bcl-2 (p-Ser70) /FITC 荧光素标记兔抗人、大、小鼠磷酸化Bcl-2抗体IgG ,英文名: Anti-Phospho-Bcl-2 ,规格: 0.2ml
Ab-(001)-04607 Anti-Bcl-6/Bcl-5/FITC 荧光素标记兔抗人、大、小鼠原癌基因Bcl-6抗体IgG ,英文名: Anti-Bcl-6/Bcl-5/FITC ,规格: 0.2ml
Ab-(001)-04608 Anti-Bcl-10/CLAP/FITC 荧光素标记兔抗人、大、小鼠Bcl-10抗体IgG ,英文名: Anti-Bcl-10/CLAP/FITC ,规格: 0.2ml
Ab-(001)-04609 Anti-Bcl-10(phospho Ser218)/FITC 荧光素标记兔抗人、大、小鼠磷酸化Bcl-10抗体IgG ,英文名: Anti-Bcl-10 ,规格: 0.2ml
Ab-(001)-04610 Anti-Bcr/CD3D/FITC 荧光素标记兔抗人、大、小鼠T淋巴细胞受体抗体IgG ,英文名: Anti-Bcr/CD3D/FITC ,规格: 0.2ml
Ab-(001)-04611 Anti-Phospho-Bcr(p-Tyr177)/FITC 荧光素标记兔抗人、大、小鼠磷酸化T淋巴细胞受体抗体IgG ,英文名: Anti-Phospho-Bcr ,规格: 0.2ml
Ab-(001)-04612 Anti-BCRP/ABCG2/BXP-21 /FITC 荧光素标记三磷酸腺苷结合转运蛋白G超家族成员2抗体IgG ,英文名: Anti-BCRP/ABCG2/BXP-21 ,规格: 0.2ml
Ab-(001)-04613 Anti-Bdkrb2/B2R/FITC 荧光素标记缓激肽B2受体抗体IgG ,英文名: Anti-Bdkrb2/B2R/FITC ,规格: 0.2ml
Ab-(001)-04614 Anti-BDNF/FITC 荧光素标记BDNF蛋白抗体IgG ,英文名: Anti-BDNF/FITC ,规格: 0.2ml
Ab-(001)-04615 Anti-BECN1/FITC 荧光素标记一种抑癌基因抗体IgG ,英文名: Anti-BECN1/FITC ,规格: 0.2ml
Ab-(001)-04616 Anti-EpCAM/CD326/FITC 荧光素标记上皮细胞特异性EpCAM/CD326蛋白抗体IgG ,英文名: Anti-EpCAM/CD326/FITC ,规格: 0.2ml
Ab-(001)-04617 Anti-Beta-casein( Beta-casein)/FITC 荧光素标记 β-酪蛋白(抗体)IgG ,英文名: Anti-Beta-casein ,规格: 0.2ml
Ab-(001)-04618 Anti-BFGF/FITC 荧光素标记碱性成纤维细胞生长因子抗体IgG ,英文名: Anti-BFGF/FITC ,规格: 0.2ml
Ab-(001)-04619 Anti-BGP/FITC 荧光素标记骨保护蛋白/骨钙素抗体IgG ,英文名: Anti-BGP/FITC ,规格: 0.2ml
Ab-(001)-04620 Anti-Bid/FITC 荧光素标记BH3结构域凋亡诱导蛋白抗体IgG ,英文名: Anti-Bid/FITC ,规格: 0.2ml
Ab-(001)-04621 Anti-AQP-2/HRP (aquaporin Protein-2) 辣根过氧化物酶标记水通道蛋白-2抗体IgG ,英文名: Anti-AQP-2/HRP ,规格: 0.2ml
Ab-(001)-04622 Anti-BIN1/FITC 荧光素标记桥连整合因子蛋白抗体IgG ,英文名: Anti-BIN1/FITC ,规格: 0.2ml
Ab-(001)-04623 Anti-Bim/FITC 荧光素标记细胞死亡调解子抗体IgG ,英文名: Anti-Bim/FITC ,磷酸化有丝分裂激酶B抗体规格: 0.2ml
Ab-(001)-04624 Anti-phospho-Bim(Ser55) /FITC 荧光素标记兔抗人、大、小鼠磷酸化细胞死亡调解子抗体IgG ,英文名: Anti-phospho-Bim ,规格: 0.2ml
Ab-(001)-04625 Anti-Bim(phospho Ser87)/FITC 荧光素标记兔抗人、大、小鼠磷酸化细胞死亡调解子抗体IgG ,英文名: Anti-Bim ,规格: 0.2ml
相关产品
详细地址
关注
拨打电话
留言咨询