供货周期: | 一周 |
品牌: | EterLife |
规格: | 0.1ml/100μg 、0.2ml/200μg |
货号: | TE-KT-0182 |
CAS号: | 详见产品说明书 |
磷酸化A-Raf抗体
〖别名〗A raf 1; A Raf proto oncogene serine/threonine protein kinase; ARAF 1; ARAF; ARaf proto oncogene serine/threonine protein kinase; ARAF1; Oncogene Araf1; Oncogene PKS2; PKS 2; PKS; PKS2; Proto oncogene Pks; RAFA 1; RAFA1; Ras binding protein DA Raf; v raf murine sarcoma 3611 viral oncogene homolog; v raf murine sarcoma 3611 viral oncogene homolog 1; v raf oncogene homolog 1 (murine sarcoma 3611 virus); ARAF_HUMAN.
〖浓度〗1mg/1ml
〖规格〗0.1ml/100μg
〖抗体来源〗Rabbit
〖克隆类型〗polyclonal
〖交叉反应〗Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit
〖产品类型〗磷酸化A-Raf抗体一抗 磷酸化抗体
〖研究领域〗肿瘤 细胞生物 染色质和核信号 神经生物学 信号转导 细胞凋亡 转录调节因子 激酶和磷酸酶 G蛋白偶联受体
〖蛋白分子量〗predicted molecular weight: 67kDa
〖性状〗Lyophilized or Liquid
〖免疫原〗KLH conjugated Synthesised phosphopeptide derived from human A Raf around the phosphorylation site of Ser214
〖亚型〗IgG
〖纯化方法〗affinity purified by Protein A
〖储存液〗0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
〖产品应用〗WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
〖保存条件〗Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
〖产品介绍〗The RAF family of signaling proteins has three isoforms: A RAF, RAF 1 and B RAF. These proteins are instrumental in forwarding the stimulus generated by mitogens from monomeric G proteins to the MAP kinase pathway. RAF 1 is known to be downstream of Ras and binds to it by an N terminal noncatalytic domain. This domain is conserved in A RAF and B RAF. 14-3-3 is also known to be an activator of RAFs. Activated RAF directly phosphorylates and activates MEK. A RAF is expressed at a very high concentration in urogenital and kidney tissues.
Function : Involved in the transduction of mitogenic signals from the cell membrane to the nucleus.
Tissue Specificity : Predominantly in urogenital tissues.
Similarity : Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.
Contains 1 phorbol-ester/DAG-type zinc finger.
Contains 1 protein kinase domain.
Contains 1 RBD (Ras-binding) domain.
Database links : UniProtKB/Swiss-Prot: P10398.2
本公司产品现货供应,货期短,质量可靠。仅用于科研实验不应用于临床。我们用专业的态度,一流的服务,全程实验指导,让你的数据不在成为实验奇谈。选择优质的磷酸化A-Raf抗体,你的小伙伴都会惊呆的。本公司专业供应各种进口、国产一抗及二抗。代理品牌有R&D、Santa Cruz、Bipec、Millipore等国际知名品牌,品种多达7000多种。让你的科研之路不再布满荆棘。
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