供货周期: | 一周 |
品牌: | EterLife |
规格: | 0.1ml/100μg 、0.2ml/200μg |
货号: | TE-KT-5076 |
CAS号: | 详见产品说明书 |
血红蛋白β抗体
〖别名〗Hemoglobin Beta; Alpha globin; Alpha-globin; Beta globin; CD113t C; CD31; Gamma 1 globin; Hb F Agamma; HBA 1; HBA 2; HBA ; HBA_HUMAN; HBA1; HBA2; HBB; Hbb-y; HBD; Hbe1; HBG 1; HBG; HBG1; HBGA; HBGR; Hemoglobin alpha 1; Hemoglobin alpha chain; Hemoglobin alpha locus; Hemoglobin beta; Hemoglobin beta chain; Hemoglobin beta chain complex; Hemoglobin beta locus; Hemoglobin gamma 1 chain; Hemoglobin gamma A; Hemoglobin gamma A chain; Hemoglobin gamma; Hemoglobin subunit alpha; Hemoglobin subunit beta; Hemoglobin subunit gamma 1.
〖浓度〗1mg/1ml
〖规格〗0.2ml/200μg
〖抗体来源〗Rabbit
〖克隆类型〗血红蛋白β抗体polyclonal
〖交叉反应〗Human
〖产品类型〗一抗
〖研究领域〗心血管 细胞生物
〖蛋白分子量〗predicted molecular weight: 15.5kDa
〖性状〗Lyophilized or Liquid
〖免疫原〗KLH conjugated synthetic peptide derived from human Hemoglobin beta
〖亚型〗IgG
〖纯化方法〗affinity purified by Protein A
〖储存液〗Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
〖产品应用〗WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
〖保存条件〗Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
〖产品介绍〗The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008].
Function : Involved in oxygen transport from the lung to the various peripheral tissues.
Tissue Specificity : Red blood cells.
Post-translational modifications : The initiator Met is not cleaved in variant Thionville and is acetylated.
DISEASE : Defects in HBA1/HBA2 may be a cause of Heinz body anemias (HEIBAN) [MIM:140700]. This is a form of non-spherocytic hemolytic anemia of Dacie type 1. After splenectomy, which has little benefit, basophilic inclusions called Heinz bodies are demonstrable in the erythrocytes. Before splenectomy, diffuse or punctate basophilia may be evident. Most of these cases are probably instances of hemoglobinopathy. The hemoglobin demonstrates heat lability.
Heinz bodies are observed also with the Ivemark syndrome (asplenia with cardiovascular anomalies) and with glutathione peroxidase deficiency.
Similarity : Belongs to the globin family.
Defects in HBA1/HBA2 are the cause of alpha-thalassemia (A-THAL) . The thalassemias are the most common monogenic diseases and occur mostly in Mediterranean and Southeast Asian populations. The hallmark of alpha-thalassemia is an imbalance in globin-chain production in the adult HbA molecule. The level of alpha chain production can range from none to very nearly normal levels. Deletion of both copies of each of the two alpha-globin genes causes alpha(0)-thalassemia, also known as homozygous alpha thalassemia. Due to the complete absence of alpha chains, the predominant fetal hemoglobin is a tetramer of gamma-chains (Bart hemoglobin) that has essentially no oxygen carrying capacity. This causes oxygen starvation in the fetal tissues leading to prenatal lethality or early neonatal death. The loss of three alpha genes results in high levels of a tetramer of four beta chains (hemoglobin H), causing a severe and life-threatening anemia known as hemoglobin H disease. Untreated, most patients die in childhood or early adolescence. The loss of two alpha genes results in mild alpha-thalassemia, also known as heterozygous alpha-thalassemia. Affected individuals have small red cells and a mild anemia (microcytosis). If three of the four alpha-globin genes are functional, individuals are completely asymptomatic. Some rare forms of alpha-thalassemia are due to point mutations (non-deletional alpha-thalassemia). The thalassemic phenotype is due to unstable globin alpha chains that are rapidly catabolized prior to formation of the alpha-beta heterotetramers.
做过实验的亲们都知道血红蛋白β抗体反应规律,仔细观察我们会发现当抗原第一次进入机体时,需经一定的潜伏期才能产生抗体,且抗体产生的量也不多,在体内维持的时间也较短。当相同抗原第二次进入机体后,开始时,由于原有抗体中的一部分与再次进入的抗原结合,可使原有抗体量略为降低。随后,抗体效价迅速大量增加,可比初次反应产生的多几倍到几十倍,在体内留存的时间亦较长。因此得出由抗原刺激机体产生的抗体,经过一定时间后可逐渐消失。此时若再次接触抗原,可使已消失的抗体快速上升。如再次刺激机体的抗原与初次相同,则称为特异性回忆反应;若与初次反应不同,则称为非特异性回忆反应。
现在很多商家都在用不同的方式为血红蛋白β抗体搞活动,做促销优惠。这需要的不仅仅是您的经验,还要您一双慧眼。商家天天在喊亏,客户天天觉得你有赚,我们喊高价,为他人做嫁衣。如今,我们不喊价,实实在在批发价零售卖。价格实在质量好,大品牌有保障,售后有服务,操作有指导。
Ab-(010)-15397 Anti-IL-1 Beta/FITC 荧光素标记白介素1β抗体IgG ,规格: 0.2ml ,英文名: Anti-IL-1
Ab-(010)-15398 Anti-IL-1 Alpha /FITC 荧光素标记白介素1α抗体IgG ,规格: 0.2ml ,英文名: Anti-IL-1
Ab-(010)-15399 Anti-phospho-IkB beta (Ser23)/FITC 荧光素标记磷酸化KB抑制蛋白β抗体IgG ,规格: 0.2ml ,英文名: Anti-phospho-IkB
Ab-(010)-15400 Anti-IKB Beta/FITC 荧光素标记KB抑制蛋白β抗体IgG ,规格: 0.2ml ,英文名: Anti-IKB
Ab-(010)-15401 Anti-IKB alpha(phospho S32 + S36)/FITC 荧光素标记磷酸化KB抑制蛋白α抗体IgG ,规格: 0.2ml ,英文名: Anti-IKB
Ab-(010)-15402 Anti-IKB Alpha/FITC 荧光素标记KB抑制蛋白α抗体IgG ,规格: 0.2ml ,英文名: Anti-IKB
Ab-(010)-15403 Anti-IGSF8/CD3/FITC 荧光素标记免疫球蛋超家族成员8抗体IgG ,规格: 0.2ml ,英文名: Anti-IGSF8/CD3/FITC
Ab-(010)-15404 Anti-IGFBP-5/IBP5 /FITC 荧光素标记胰岛素样生长因子结合蛋白-5抗体IgG ,规格: 0.2ml ,英文名: Anti-IGFBP-5/IBP5
Ab-(010)-15405 Anti-IGFBP-4/IBP4/FITC 荧光素标记胰岛素样生长因子结合蛋白-4抗体IgG ,规格: 0.2ml ,英文名: Anti-IGFBP-4/IBP4/FITC
Ab-(010)-15406 Anti-IGFBP-3/FITC 荧光素标记胰岛素样生长因子结合蛋白-3抗体IgG ,规格: 0.2ml ,英文名: Anti-IGFBP-3/FITC
Ab-(010)-15407 Anti-IGFBP-2/FITC 荧光素标记胰岛素样生长因子结合蛋白-2抗体IgG ,规格: 0.2ml ,英文名: Anti-IGFBP-2/FITC
Ab-(010)-15408 Anti-IGFBP-1/FITC 荧光素标记胰岛素样生长因子结合蛋白-1抗体IgG ,规格: 0.2ml ,英文名: Anti-IGFBP-1/FITC
Ab-(010)-15409 Anti-phospho-IGF1 Receptor (Tyr1161) /FITC 荧光素标记磷酸化胰岛素样生长因子1受体抗体IgG ,规格: 0.2ml ,英文名: Anti-phospho-IGF1
Ab-(010)-15410 Anti-IGF-1R/FITC 荧光素标记胰岛素样生长因子-I受体抗体IgG ,规格: 0.2ml ,英文名: Anti-IGF-1R/FITC
Ab-(010)-15411 Anti-IGF-1 R/FITC 荧光素标记胰岛素样生长因子-I受体抗体IgG ,规格: 0.2ml ,英文名: Anti-IGF-1
Ab-(010)-15412 Anti-IGF-IIBP3/FITC 荧光素标记胰岛素样生长因子2 mRNA 结合蛋白3抗体IgG ,规格: 0.2ml ,英文名: Anti-IGF-IIBP3/FITC
Ab-(010)-15413 Anti-IGF-II/FITC 荧光素标记胰岛素样生长因子-II抗体IgG ,规格: 0.2ml ,英文名: Anti-IGF-II/FITC
Ab-(010)-15414 Anti-IGF-I/FITC 荧光素标记标记胰岛素样生长因子-I抗体IgG ,规格: 0.2ml ,英文名: Anti-IGF-I/FITC
Ab-(010)-15415 Anti-IGC/FITC 荧光素标记兔抗非洲爪蟾IGC抗体IgG ,规格: 0.2ml ,英文名: Anti-IGC/FITC
Ab-(010)-15416 Anti-IFNGR1/CD119/FITC 荧光素标记干扰素-gamma受体抗体IgG ,规格: 0.2ml ,英文名: Anti-IFNGR1/CD119/FITC
Ab-(010)-15417 Anti-IFN- Gamma/HRP 辣根过氧化物酶标记鼠抗人干扰素-γ/IFN-gamma单克隆抗体IgG ,规格: 0.2ml ,英文名: Anti-IFN-
Ab-(010)-15418 Anti-IFNGR2/FITC 荧光素标记干扰素-gamma受体2抗体IgG ,规格: 0.2ml ,英文名: Anti-IFNGR2/FITC
Ab-(010)-15419 Anti-IFN- Gamma/FITC(Interferon Gamma) 荧光素标记抗大、小鼠IFN-γ抗IgG ,规格: 0.2ml ,英文名: Anti-IFN-
Ab-(010)-15420 Anti-IFN- Gamma/FITC 荧光素标记干扰素-γ抗体IgG ,规格: 0.2ml ,英文名: Anti-IFN-
Ab-(010)-15421 Anti-IFN- Beta/FITC 荧光素标记抗人干扰素-β抗IgG ,规格: 0.2ml ,英文名: Anti-IFN-
Ab-(010)-15422 Anti-IFN- Beta/FITC 荧光素标记干扰素-β抗体IgG ,规格: 0.2ml ,英文名: Anti-IFN-
Ab-(010)-15423 Anti-human IFN- Alpha /FITC 荧光素标记干扰素-α抗体(抗人)IgG ,规格: 0.2ml ,英文名: Anti-human
Ab-(010)-15424 Anti-IFITM1/FITC 荧光素标记干扰素诱导跨膜蛋白1抗体IgG ,规格: 0.2ml ,英文名: Anti-IFITM1/FITC
Ab-(010)-15425 Anti-IFI16/p16 /FITC 荧光素标记γ干扰素诱导蛋白16抗体IgG ,规格: 0.2ml ,英文名: Anti-IFI16/p16
Ab-(010)-15426 Anti-IFABP/FITC 荧光素标记小肠型脂肪酸结合蛋白抗体IgG ,规格: 0.2ml ,英文名: Anti-IFABP/FITC
Ab-(010)-15427 Anti-IFABP/FITC 荧光素标记小肠型脂肪酸结合蛋白抗体IgG ,规格: 0.2ml ,英文名: Anti-IFABP/FITC
Ab-(010)-15428 Anti-IDE/FITC 荧光素标记胰岛素降解酶抗体IgG ,规格: 0.2ml ,英文名: Anti-IDE/FITC
Ab-(010)-15429 Anti-ID1/Inhibitor of DNA binding 1 /FITC 荧光素标记DNA结合抑制因子1抗体IgG ,规格: 0.2ml ,英文名: Anti-ID1/Inhibitor
Ab-(010)-15430 Anti-IDE/FITC 荧光素标记胰岛素降解酶抗体IgG ,规格: 0.2ml ,英文名: Anti-IDE/FITC
Ab-(010)-15431 Anti-ICOS-L/B7-H2/CD275/FITC 荧光素标记诱导协同刺激分子配体CD275抗体IgG ,规格: 0.2ml ,英文名: Anti-ICOS-L/B7-H2/CD275/FITC
Ab-(010)-15432 Anti-Icos/CD278/FITC 荧光素标记诱导协同刺激分子CD278抗体IgG ,规格: 0.2ml ,英文名: Anti-Icos/CD278/FITC
Ab-(010)-15433 Anti-ICAM-3/CD50/FITC 荧光素标记细胞间粘附分子-3抗体IgG ,规格: 0.2ml ,英文名: Anti-ICAM-3/CD50/FITC
Ab-(010)-15434 Anti-CD54/ICAM-1/Biotin 生物素标记细胞间粘附分子-1抗体IgG ,规格: 0.2ml ,英文名: Anti-CD54/ICAM-1/Biotin
Ab-(010)-15435 Anti-ICAM-1(CD54)/FITC 荧光素标记细胞间粘附分子-1抗体IgG ,规格: 0.2ml ,英文名: Anti-ICAM-1
Ab-(010)-15436 Anti-ICAD/FITC 荧光素标记Caspase 激活的脱氧核糖核酸酶抑制剂抗体IgG ,规格: 0.2ml ,英文名: Anti-ICAD/FITC
Ab-(010)-15437 Anti-Iba-1/FITC 荧光素标记离子钙接头蛋白抗体IgG ,规格: 0.2ml ,英文名: Anti-Iba-1/FITC
Ab-(010)-15438 Anti-IASPP/FITC 荧光素标IASPP蛋白抗体IgG ,规格: 0.2ml ,英文名: Anti-IASPP/FITC
Ab-(010)-15439 Anti-IAA/FITC 荧光素标记吲哚-3-乙酸抗体/植物生长素单克隆抗体IgG ,规格: 0.2ml ,英文名: Anti-IAA/FITC
Ab-(010)-15440 Anti-IAA/FITC 荧光素标记吲哚-3-乙酸抗体/植物生长素抗体IgG ,规格: 0.2ml ,英文名: Anti-IAA/FITC
Ab-(010)-15441 Anti-COX10/FITC 荧光素标记COX10抗体IgG ,规格: 0.2ml ,英文名: Anti-COX10/FITC
Ab-(010)-15442 Anti-TRT/TERT/PE 荧光素PE标记端粒酶抗体IgG ,规格: 0.2ml ,英文名: Anti-TRT/TERT/PE
Ab-(010)-15443 Anti-TRT/FITC 荧光素标记端粒酶抗体IgG ,规格: 0.2ml ,英文名: Anti-TRT/FITC
Ab-(010)-15444 Anti-HtrA2/Omi/FITC 荧光素标记丝氨酸蛋白酶/线粒体丝氨酸蛋白酶抗体IgG ,规格: 0.2ml ,英文名: Anti-HtrA2/Omi/FITC
Ab-(010)-15445 Anti-HSTF2/HSF2 /FITC 荧光素标记热休克转录因子2抗体IgG ,规格: 0.2ml ,英文名: Anti-HSTF2/HSF2
Ab-(010)-15446 Anti-HSP-105/FITC 荧光素标记热休克蛋白HSP105抗体IgG ,规格: 0.2ml ,英文名: Anti-HSP-105/FITC
Ab-(010)-15447 Anti-HSP27/RBITC 红色荧光素罗丹明标记热休克蛋白-27抗体IgG ,规格: 0.2ml ,英文名: Anti-HSP27/RBITC
Ab-(010)-15448 Anti-HSP-90 Beta/FITC 荧光素标记HSP-90β蛋白抗体IgG ,规格: 0.2ml ,英文名: Anti-HSP-90
Ab-(010)-15449 Anti-HSP-90 Alpha/FITC 荧光素标记热休克蛋白90α抗体IgG ,规格: 0.2ml ,英文名: Anti-HSP-90
Ab-(010)-15450 Anti-HSP-90 Alpha/FITC 荧光素标记HSP-90α蛋白抗体IgG ,规格: 0.2ml ,英文名: Anti-HSP-90
Ab-(010)-15451 Anti-OMPC/OMPA/FITC 荧光素标记抗大肠杆菌外膜孔道蛋白C抗体IgG ,规格: 0.2ml ,英文名: Anti-OMPC/OMPA/FITC
Ab-(010)-15452 Anti-HSP75/TRAP-1 /FITC 荧光素标记热休克蛋白-75抗体IgG ,规格: 0.2ml ,血红蛋白β抗体英文名: Anti-HSP75/TRAP-1
Ab-(010)-15453 Anti-HSP-70/FITC 荧光素标记HSP-70蛋白抗体IgG ,规格: 0.2ml ,英文名: Anti-HSP-70/FITC
Ab-(010)-15454 Anti-HSP-60/FITC 荧光素标记热休克蛋白-60蛋白抗体IgG ,规格: 0.2ml ,英文名: Anti-HSP-60/FITC
相关产品
详细地址
关注
拨打电话
留言咨询