供货周期: | 一周 |
品牌: | EterLife |
规格: | 0.1ml/100μg 、0.2ml/200μg |
货号: | TE-KT-5087 |
CAS号: | 详见产品说明书 |
组蛋白替换精蛋白DGGR1抗体
〖别名〗DGCR1; DGGR 1; DGGR1; DiGeorge critical region gene 1; HIR; HIR histone cell cycle regulation defective homolog A; HIRA; HIRA protein; HIRA_HUMAN; Protein HIRA; TUP 1; TUP1; TUP1 like enhancer of split protein 1; TUP1-like enhancer of split protein 1; TUPLE 1; TUPLE1.
〖浓度〗1mg/1ml
〖规格〗0.1ml/100μg 0.2ml/200μg
〖抗体来源〗Rabbit
〖克隆类型〗polyclonal
〖交叉反应〗组蛋白替换精蛋白DGGR1抗体Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit
〖产品类型〗一抗
〖研究领域〗细胞生物 免疫学 发育生物学 染色质和核信号 干细胞 通道蛋白 细胞类型标志物 表观遗传学
〖蛋白分子量〗predicted molecular weight: 112kDa
〖性状〗Lyophilized or Liquid
〖免疫原〗KLH conjugated synthetic peptide derived from human HIRA/DGGR1
〖亚型〗IgG
〖纯化方法〗affinity purified by Protein A
〖储存液〗0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
〖产品应用〗WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
〖保存条件〗Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
〖产品介绍〗The HIRA gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in flies, yeast and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.
Function : Cooperates with ASF1A to promote replication-independent chromatin assembly. Required for the periodic repression of histone gene transcription during the cell cycle. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
Subunit : Interacts with histone H3F3B, PAX3 and PAX7 (By similarity). Interacts with CCNA1, HIRIP3, NFU1/HIRIP5 and histone H2B. Part of a complex which includes ASF1A, CABIN1, histone H3.3, histone H4 and UBN1.
Subcellular Location : Nucleus. Nucleus, PML body. Note=Primarily, though not exclusively, localized to the nucleus. Localizes to PML bodies immediately prior to onset of senescence.
Tissue Specificity : Expressed at high levels in kidney, pancreas and skeletal muscle and at lower levels in brain, heart, liver, lung, and placenta.
Post-translational modifications : Sumoylated.
Phosphorylated by CDK2/CCNA1 and CDK2/CCNE1 on Thr-555 in vitro. Also phosphorylated on Thr-555 and Ser-687 in vivo.
Similarity : Belongs to the WD repeat HIR1 family.
Contains 8 WD repeats.
Database links : UniProtKB/Swiss-Prot: P54198.2
做过实验的亲们都知道组蛋白替换精蛋白DGGR1抗体反应规律,仔细观察我们会发现当抗原第一次进入机体时,需经一定的潜伏期才能产生抗体,且抗体产生的量也不多,在体内维持的时间也较短。当相同抗原第二次进入机体后,开始时,由于原有抗体中的一部分与再次进入的抗原结合,可使原有抗体量略为降低。随后,抗体效价迅速大量增加,可比初次反应产生的多几倍到几十倍,在体内留存的时间亦较长。因此得出由抗原刺激机体产生的抗体,经过一定时间后可逐渐消失。此时若再次接触抗原,可使已消失的抗体快速上升。如再次刺激机体的抗原与初次相同,则称为特异性回忆反应;若与初次反应不同,则称为非特异性回忆反应。
现在很多商家都在用不同的方式为组蛋白替换精蛋白DGGR1抗体搞活动,做促销优惠。这需要的不仅仅是您的经验,还要您一双慧眼。商家天天在喊亏,客户天天觉得你有赚,我们喊高价,为他人做嫁衣。如今,我们不喊价,实实在在批发价零售卖。价格实在质量好,大品牌有保障,售后有服务,操作有指导。
Ab-(010)-15959 Anti-Dectin-2/CLECSF10/CLEC6A/FITC 荧光素标记C型凝集素结构域家族6成员A抗体IgG ,规格: 0.2ml ,英文名: Anti-Dectin-2/CLECSF10/CLEC6A/FITC
Ab-(010)-15960 Anti-Dectin-1/CLECSF12/FITC 荧光素标记C型凝集素结构域家族7成员A抗体IgG ,规格: 0.2ml ,英文名: Anti-Dectin-1/CLECSF12/FITC
Ab-(010)-15961 Anti-DEC-205/CD205/Ly75/FITC 荧光素标记CD205抗体IgG ,规格: 0.2ml ,英文名: Anti-DEC-205/CD205/Ly75/FITC
Ab-(010)-15962 Anti-DDC/FITC 荧光素标记多巴铵脱羧酶抗体IgG ,规格: 0.2ml ,英文名: Anti-DDC/FITC
Ab-(010)-15963 Anti-DDB2/FITC 荧光素标记损伤DNA结合蛋白2抗体IgG ,规格: 0.2ml ,英文名: Anti-DDB2/FITC
Ab-(010)-15964 Anti-DDB1/FITC 荧光素标记损伤DNA结合蛋白1抗体IgG ,规格: 0.2ml ,英文名: Anti-DDB1/FITC
Ab-(010)-15965 Anti-DDAH-II /FITC 荧光素标记双甲基精氨酸水解酶2抗体IgG ,规格: 0.2ml ,英文名: Anti-DDAH-II
Ab-(010)-15966 Anti-D-DIMER/FITC 荧光素标记交联纤维蛋白二聚体抗体IgG ,规格: 0.2ml ,英文名: Anti-D-DIMER/FITC
Ab-(010)-15967 Anti-Phospho-Doublecortin (Ser297) /FITC 荧光素标记兔抗人、大、小鼠等磷酸化双皮质素抗体IgG ,规格: 0.2ml ,英文名: Anti-Phospho-Doublecortin
Ab-(010)-15968 Anti-DCX/FITC 荧光素标记双皮质素抗体IgG ,规格: 0.2ml ,英文名: Anti-DCX/FITC
Ab-(010)-15969 Anti-DCP /HRP 辣根过氧化物酶标记异常凝血酶原/脱-γ-羧基凝血酶原抗体IgG ,规格: 0.2ml ,英文名: Anti-DCP
Ab-(010)-15970 Anti-DCP/FITC 荧光素标记异常凝血酶原/脱-γ-羧基凝血酶原抗体IgG ,规格: 0.2ml ,英文名: Anti-DCP/FITC
Ab-(010)-15971 Anti-DCN/FITC 荧光素标记抗核心蛋白聚糖抗体IgG ,规格: 0.2ml ,英文名: Anti-DCN/FITC
Ab-(010)-15972 Anti-DCIR/CLEC4A/FITC 荧光素标记C型凝集素结构域家族4成员A抗体IgG ,规格: 0.2ml ,英文名: Anti-DCIR/CLEC4A/FITC
Ab-(010)-15973 Anti-DC-SIGNR/CD299/FITC 荧光素标记CD299抗体IgG ,规格: 0.2ml ,英文名: Anti-DC-SIGNR/CD299/FITC
Ab-(010)-15974 Anti-DC-SIGN/CD209/CLEC4L/FITC 荧光素标记CD209抗体IgG ,规格: 0.2ml ,英文名: Anti-DC-SIGN/CD209/CLEC4L/FITC
Ab-(010)-15975 Anti-DC-LAMP/LAMP-3/CD208/FITC 荧光素标记CD208抗体IgG ,规格: 0.2ml ,英文名: Anti-DC-LAMP/LAMP-3/CD208/FITC
Ab-(010)-15976 Anti-DCC/FITC 荧光素标记兔抗结直肠癌缺失基因抗体IgG ,规格: 0.2ml ,英文名: Anti-DCC/FITC
Ab-(010)-15977 Anti-DBH /FITC 荧光素标记多巴铵β羟化酶抗体IgG ,规格: 0.2ml ,英文名: Anti-DBH
Ab-(010)-15978 Anti-DAT1/FITC 荧光素标记抗多巴铵相关转录因子1抗体IgG ,规格: 0.2ml ,英文名: Anti-DAT1/FITC
Ab-(010)-15979 Anti-Crk p38 (phospho Y221) /FITC 荧光素标记兔抗人、大、小鼠磷酸化Crk p38抗体IgG ,规格: 0.2ml ,英文名: Anti-Crk
Ab-(010)-15980 Anti-phospho-Cyclin E(Thr395) /FITC 荧光素标记兔抗人、大、小鼠磷酸化周期素E抗体IgG ,规格: 0.2ml ,英文名: Anti-phospho-Cyclin
Ab-(010)-15981 Anti-Phospho-DARPP32 (Thr75) /FITC 荧光素标记兔抗人、大、小鼠磷酸化多巴铵、cAMP调节磷蛋白抗体IgG ,规格: 0.2ml ,英文名: Anti-Phospho-DARPP32
Ab-(010)-15982 Anti-Phospho-DARPP32 (Thr34) /FITC 荧光素标记兔抗人、大、小鼠磷酸化多巴铵、cAMP调节磷蛋白抗体IgG ,规格: 0.2ml ,英文名: Anti-Phospho-DARPP32
Ab-(010)-15983 Anti-DARPP32/FITC 荧光素标记兔抗人、大、小鼠多巴铵、cAMP调节磷蛋白抗体IgG ,规格: 0.2ml ,英文名: Anti-DARPP32/FITC
Ab-(010)-15984 Anti-DAPK3/FITC 荧光素标记凋亡相关蛋白激酶3抗体IgG ,规格: 0.2ml ,英文名: Anti-DAPK3/FITC
Ab-(010)-15985 Anti-DAPK2/FITC 荧光素标记凋亡相关蛋白激酶2抗体IgG ,规格: 0.2ml ,英文名: Anti-DAPK2/FITC
Ab-(010)-15986 Anti-DAPK1/FITC 荧光素标记凋亡相关蛋白激酶1抗体IgG ,规格: 0.2ml ,英文名: Anti-DAPK1/FITC
Ab-(010)-15987 Anti-DBC1/FITC 荧光素标记兔抗人、大、小鼠膀胱癌缺失基因1抗体IgG ,规格: 0.2ml ,英文名: Anti-DBC1/FITC
Ab-(010)-15988 Anti-DAP-5/p97 /FITC 荧光素标记死亡相关蛋白5抗体IgG ,规格: 0.2ml ,英文名: Anti-DAP-5/p97
Ab-(010)-15989 Anti-Phospho-DBC1 (Thr454) /FITC 荧光素标记兔抗人、大、小鼠磷酸化膀胱癌缺失基因1IgG ,规格: 0.2ml ,英文名: Anti-Phospho-DBC1
Ab-(010)-15990 Anti-Phospho-Dab1 (Ser491) /FITC 荧光素标记兔抗人、大、小鼠磷酸化Disabled 1抗体IgG ,规格: 0.2ml ,英文名: Anti-Phospho-Dab1
Ab-(010)-15991 Anti-Phospho-Dab1 (Tyr232) /FITC 荧光素标记兔抗人、大、小鼠磷酸化Disabled 1抗体IgG ,规格: 0.2ml ,英文名: Anti-Phospho-Dab1
Ab-(010)-15992 Anti-Phospho-Dab1 (Tyr220) /FITC 荧光素标记兔抗人、大、小鼠磷酸化Disabled 1抗体IgG ,规格: 0.2ml ,英文名: Anti-Phospho-Dab1
Ab-(010)-15993 Anti-DRD5 receptor/FITC 荧光素标记抗多巴铵受体-D5抗体IgG ,规格: 0.2ml ,英文名: Anti-DRD5
Ab-(010)-15994 Anti-DRD4 receptor/FITC 荧光素标记抗多巴铵受体-D4抗体IgG ,规格: 0.2ml ,英文名: Anti-DRD4
Ab-(010)-15995 Anti-DRD3 receptor/FITC 荧光素标记多巴铵受体-D3抗体IgG ,规格: 0.2ml ,英文名: Anti-DRD3
Ab-(010)-15996 Anti-DRD2 receptor/FITC 荧光素标记多巴铵受体-D2抗体IgG ,规格: 0.2ml ,英文名: Anti-DRD2
Ab-(010)-15997 Anti-DRD1 receptor/FITC 荧光素标记多巴铵受体-D1抗体IgG ,规格: 0.2ml ,英文名: Anti-DRD1
Ab-(010)-15998 Anti-CK1/8/19(Cytokeratin 1/8/19)/FITC 荧光素标记细胞角蛋白抗体1/8/19IgG ,规格: 0.2ml ,英文名: Anti-CK1/8/19
Ab-(010)-15999 Anti-Cytochrome P450 2D6/CYP2D6 /FITC 荧光素标记细胞色素P450 2D6抗体IgG ,规格: 0.2ml ,英文名: Anti-Cytochrome
Ab-(010)-16000 Anti-Cytochrome P450 2C9/CYP2C9 /FITC 荧光素标记细胞色素P450 2C9抗体IgG ,规格: 0.2ml ,英文名: Anti-Cytochrome
Ab-(010)-16001 Anti-Cytochrome P450 2C19/CYP2C19 /FITC 荧光素标记细胞色素P450 2C19抗体IgG ,规格: 0.2ml ,英文名: Anti-Cytochrome
Ab-(010)-16002 Anti-Cytochrome C/FITC 荧光素标记细胞色素 C抗体IgG ,规格: 0.2ml ,英文名: Anti-Cytochrome
Ab-(010)-16003 Anti-Cyr61/FITC 荧光素标记富半胱氨酸肝素结合蛋白61IgG ,规格: 0.2ml ,英文名: Anti-Cyr61/FITC
Ab-(010)-16004 Anti-CYP21/FITC 荧光素标记21-羟化酶抗体IgG ,规格: 0.2ml ,组蛋白替换精蛋白DGGR1抗体英文名: Anti-CYP21/FITC
Ab-(010)-16005 Anti-CYP19/FITC 荧光素标记细胞色素P450 19抗体IgG ,规格: 0.2ml ,英文名: Anti-CYP19/FITC
Ab-(010)-16006 Anti-CYP8A1/PTGIS/FITC 荧光素标记前列环素合成酶抗体IgG ,规格: 0.2ml ,英文名: Anti-CYP8A1/PTGIS/FITC
相关产品
详细地址
关注
拨打电话
留言咨询