供货周期: | 一周 |
品牌: | EterLife |
规格: | 0.1ml/100μg 、0.2ml/200μg |
货号: | TE-KT-5093 |
CAS号: | 详见产品说明书 |
肺癌相关蛋白Y抗体
〖别名〗SMAP31; CAMEO; HOD; Homeodomain-only protein; HOP; HOP homeobox; HOP_HUMAN; HOPX; LAGY; Lung cancer-associated Y protein; NECC1; Not expressed in choriocarcinoma clone 1; Not expressed in choriocarcinoma protein 1; Odd homeobox protein 1; TOTO.
〖浓度〗1mg/1ml
〖规格〗0.2ml/200μg
〖抗体来源〗Rabbit
〖克隆类型〗polyclonal
〖交叉反应〗肺癌相关蛋白Y抗体Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep
〖产品类型〗一抗
〖研究领域〗肿瘤 心血管 转录调节因子 表观遗传学
〖蛋白分子量〗predicted molecular weight: 8kDa
〖性状〗Lyophilized or Liquid
〖免疫原〗KLH conjugated synthetic peptide derived from human HOPX/LAGY
〖亚型〗IgG
〖纯化方法〗affinity purified by Protein A
〖储存液〗Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
〖产品应用〗ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
〖保存条件〗Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
〖产品介绍〗Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor.
Function : Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor.
Subunit : Interacts with serum response factor (SRF). Component of a large complex containing histone deacetylases such as HDAC2 (By similarity).
Subcellular Location : Nucleus.
Tissue Specificity : Widely expressed. Expressed in the heart, brain, placenta, lung, skeletal and smooth muscles, uterus, urinary bladder, kidney and spleen. Down-regulated in some types of cancer such as lung cancer, choriocarcinoma, head and neck squamous cell carcinoma and oral squamous cell carcinoma.
Similarity : Contains 1 homeobox DNA-binding domain.
Database links : UniProtKB/Swiss-Prot: Q9BPY8.1
做过实验的亲们都知道肺癌相关蛋白Y抗体反应规律,仔细观察我们会发现当抗原第一次进入机体时,需经一定的潜伏期才能产生抗体,且抗体产生的量也不多,在体内维持的时间也较短。当相同抗原第二次进入机体后,开始时,由于原有抗体中的一部分与再次进入的抗原结合,可使原有抗体量略为降低。随后,抗体效价迅速大量增加,可比初次反应产生的多几倍到几十倍,在体内留存的时间亦较长。因此得出由抗原刺激机体产生的抗体,经过一定时间后可逐渐消失。此时若再次接触抗原,可使已消失的抗体快速上升。如再次刺激机体的抗原与初次相同,则称为特异性回忆反应;若与初次反应不同,则称为非特异性回忆反应。
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Ab-(010)-16274 Anti-CD158e/KIR3DL1/FITC 荧光素标记NK细胞抑制性受体3DL1抗体IgG ,规格: 0.2ml ,英文名: Anti-CD158e/KIR3DL1/FITC
Ab-(010)-16275 Anti-CD158D/KIR2DL4/G9P/FITC 荧光素标记NK细胞抑制性受体2DL4抗体IgG ,规格: 0.2ml ,英文名: Anti-CD158D/KIR2DL4/G9P/FITC
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Ab-(010)-16277 Anti-CD158a/KIR2DL1/FITC 荧光素标记NK细胞抑制性受体2DL1抗体IgG ,规格: 0.2ml ,英文名: Anti-CD158a/KIR2DL1/FITC
Ab-(010)-16278 Anti-CD146(MCAN)/FITC 荧光素标记抗黑色素瘤细胞粘付分子CD146抗体IgG ,规格: 0.2ml ,英文名: Anti-CD146
Ab-(010)-16279 Anti-VE-cadherin/CD144/VECD/FITC 荧光素标记上皮型钙粘附分子/血管内皮钙粘蛋白抗体IgG ,规格: 0.2ml ,英文名: Anti-VE-cadherin/CD144/VECD/FITC
Ab-(010)-16280 Anti-CD141/FITC 荧光素标记凝血调节蛋白抗体IgG ,规格: 0.2ml ,英文名: Anti-CD141/FITC
Ab-(010)-16281 Anti-Syndecan-1/CD138/FITC 荧光素标记多配体聚糖抗体IgG ,规格: 0.2ml ,英文名: Anti-Syndecan-1/CD138/FITC
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Ab-(010)-16286 Anti-OX40/CD134/TNFRSF4/FITC 荧光素标记CD134抗体IgG ,规格: 0.2ml ,英文名: Anti-OX40/CD134/TNFRSF4/FITC
Ab-(010)-16287 Anti-CD133 Anti-gen/FITC 荧光素标记造血干细胞抗原CD133抗体IgG ,规格: 0.2ml ,英文名: Anti-CD133
Ab-(010)-16288 Anti-CD117/FITC 荧光素标记CD117抗体IgG ,规格: 0.2ml ,英文名: Anti-CD117/FITC
Ab-(010)-16289 Anti-nectin 2/CD112/FITC 荧光素标记细胞黏附分子CD112抗体IgG ,规格: 0.2ml ,英文名: Anti-nectin
Ab-(010)-16290 Anti-CD107a/LAMP-1/PE 荧光素PE标记溶酶体相关膜蛋白1抗体IgG ,规格: 0.2ml ,英文名: Anti-CD107a/LAMP-1/PE
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Ab-(010)-16296 Anti-CD86/B7-2 /FITC 荧光素标记CD86抗体IgG ,规格: 0.2ml ,英文名: Anti-CD86/B7-2
Ab-(010)-16297 Anti-SLAMF6/LY108/FITC 荧光素标记SLAMF6抗体IgG ,规格: 0.2ml ,英文名: Anti-SLAMF6/LY108/FITC
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Ab-(010)-16299 Anti-CD83/Cell surface protein HB15/FITC 荧光素标记CD83抗体IgG ,规格: 0.2ml ,英文名: Anti-CD83/Cell
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