供货周期: | 现货 |
品牌: | GenWay |
规格: | 0.2ml/200μg |
货号: | |
CAS号: |
TBR1蛋白抗体浓 度 1mg/1ml
规 格 0.2ml/200μg
英文名称 Anti-TBR1
中文名称 TBR1蛋白抗体
别 名 A novel murine and human gene, TBR-1, encodes a putative transcription factor related to the Brachyrury (T) gene that is expressed only in postmitotic cells. T-brain-1 (TBR-1) mRNA is largely restricted to the cerebral cortex, where, during embryogenesis, it defines different regions that give rise to the palecortex, limbic cortex and neocortex (1-3). TBR-1, Pax-6 and Emx-1 are expressed in the mouse and chicken pallium. The pallio-subpallial boundary lies at the interface between the TBR-1 and Dlx-2 expression domains. Chicken genes homolgous to these mouse genes are expressed in topologically comparable patterns during development, suggesting that mouse and chicken may have similar histogenetic specification processes and field homologies (4). CASK/LIN-2, a membrane-associated guanylate kinase, is required for EGFR localization and signaling. In adult rat brain, CASK is concentrated at neuronal synapses and binds to the cell-surface proteins. CASK can interact with TBR-1, which is involved in forebrain development. CASK enters into the nucleus and binds to a specific DNA sequence (the T-element) in a complex with TBR-1. Thus, CASK acts as a coactivator of TBR-1 to induce transcription of T-element containing genes, including reelin (5); TBR1_HUMAN.
抗体来源 Rabbit
TBR1蛋白抗体单抗的标记目前动物用单抗,在动物疫病诊断和检疫、妊娠检测、性别鉴定等方面有广泛的应用,大多以诊断试剂(盒)的形式提供,其中核心试剂为标记的单抗。下面将介绍TBR1蛋白抗体最常用的几种标记技术。
(1) 酶标记A、 辣根过氧化物酶(HRP)标记辣根过氧化物酶(HRP)标记单抗和多克隆抗体的常用方法是过碘酸钠法。其原理是HRP的糖基用过碘酸钠氧化成醛基,加入抗体IgG后该醛基与IgG氨基结合,形成Schiff氏碱。为了防止HRP中糖的醛基与其自身蛋白氨基发生偶合,在用过碘酸钠氧化前先用二硝基氟苯阻断氨基。氧化反应末了,用硼氢化钠稳定Schiff氏碱。
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep
产品类型 一抗
研究领域 细胞生物 神经生物学 信号转导
蛋白分子量 predicted molecular weight: 74kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human TBR1 (35-130aa)
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
CCL12/MCP-5(C-C motif chemokine 12) 单核细胞趋化蛋白5抗原 Multi-class antibodies 规格: 0.5mg
CCL14/HCC-1(C-C motif chemokine 14) 嗜酸粒细胞趋化蛋白14抗原 Multi-class antibodies 规格: 0.5mg
ABCD-1/CCL22 嗜酸粒细胞趋化蛋白22抗原 Multi-class antibodies 规格: 0.2mg
MIP-3 beta/ELC/CCL19(Macrophage Inflammatory Protein 3 Beta) 巨噬细胞炎性蛋白19抗原 Multi-class antibodies 规格: 0.5mg
CCL26(Eotaxin 3) 嗜酸粒细胞趋化蛋白3抗原 Multi-class antibodies 规格: 0.5mg
CCR-1(CC chemokine receptor 1) 细胞表面趋化因子受体1抗原 Multi-class antibodies 规格: 0.5mg
CCR-3(CC chemokine receptor 3) CC趋化因子受体3抗原 Multi-class antibodies 规格: 0.5mg
CCR-2A(C-C Chemokine receptor 2A) 细胞表面趋化因子受体2A抗原 Multi-class antibodies 规格: 0.5mg
CCR-4(C-C chemokine receptor 4) 细胞表面趋化因子受体4抗原 Multi-class antibodies 规格: 0.5mg
CCR-6/CD196 peptide 细胞表面趋化因子受体6抗原 Multi-class antibodies 规格: 0.5mg
CXCR6(CXC-chemokine receptor 6) peptide 细胞表面趋化因子受体6抗原 Multi-class antibodies 规格: 0.5mg
CCR-7(CC chemokine receptor 7) CC趋化因子受体7(多肽) Multi-class antibodies 规格: 0.5mg
CXCL10/IP-10 CXCL10趋化因子10/干扰素诱导蛋白10抗原 Multi-class antibodies 规格: 0.5mg
VEGF(Vascular endothelial growth factor) 血管内皮生长因子(多肽抗原) Multi-class antibodies 规格: 0.5mg
CD10/CALLA (Neutral Endopeptidase) CD10抗原 Multi-class antibodies 规格: 0.5mg
ZCWCC1(Zinc finger CW-type coiled-coil domain protein 1) ZCWCC1抗原 Multi-class antibodies 规格: 0.5mg
CD105/Endoglin/TGF- Beta receptor CD105/转化生长因子β受体抗原 Multi-class antibodies 规格: 0.5mg
CD138/Syndecan-1 多配体蛋白聚糖1抗原 Multi-class antibodies 规格: 0.5mg
CD146/MCAM 黑色素瘤细胞粘附分子CD146抗原 Multi-class antibodies 规格: 0.5mg
ANPEN/CD13(Aminopeptidase N) 氨肽酶N抗原 Multi-class antibodies 规格: 0.5mg
CD14(cluster of differentiation antigen 14) CD14/内毒素受体抗原 Multi-class antibodies 规格: 0.5mg
TBR1蛋白抗体CD28 CD28抗原 Multi-class antibodies 规格: 0.5mg
CD166/ALCAM(activated leukocyte celladhesion molecule) 活化白细胞粘附分子抗原 Multi-class antibodies 规格: 0.5mg
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