供货周期: | 现货 |
品牌: | GenWay |
规格: | 0.1ml/100μg |
货号: | yy01-0069 |
CAS号: |
磷酸化细胞信号转导分子SMAD3抗体形态:液态
抗体纯度: >95% By SDS-PAGE
保存环境:2-8℃ 短期保存或<-20℃长期保存保存 1 年以上,避免反复冻融。
英文名称 Anti-phospho-Smad3 (Ser423)
中文名称 磷酸化细胞信号转导分子SMAD3抗体
别 名 Smad3 (phospho Ser423); Smad3 (phospho S423); p-Smad3 (Ser423); hMAD 3; hSMAD3; HSPC193; JV15 2; JV152; MAD (mothers against decapentaplegic Drosophila) homolog 3; MAD3; MADH 3; MADH3; Mothers against decapentaplegic homolog 3; Mothers against DPP homolog 3; SMA and MAD related protein 3; SMAD 3; SMAD; SMAD-3; SMAD3_HUMAN.
浓 度 1mg/1ml
磷酸化细胞信号转导分子SMAD3抗体规 格 0.1ml/100μg
我们提供抗体来源有人、小鼠、大鼠、兔等动物,规格多样,全国免邮,我们用更安全的方式方法保存及运输磷酸化细胞信号转导分子SMAD3抗体。
本公司专业供应各种进口、国产一抗及二抗,品牌有R&D、Santa Cruz、Bipec、Millipore等国际知名品牌,品种多达7000多种,由于产品的数量众多,产品的宿主、抗原来源及应用范围(WB、IH(F/P)、FC、ELISA、IP、IF等)有所不同。
我们还可以为客户提供BAP31蛋白抗体的纯化和标记服务,具体包括盐析沉淀纯化、Portein A/G纯化、免疫亲和纯化、HRP标记、FITC标记等。
磷酸化细胞信号转导分子SMAD3抗体的详细介绍:
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Pig
产品类型 一抗 磷酸化抗体
研究领域 肿瘤 细胞生物 信号转导 干细胞 细胞凋亡 生长因子和激素 转录调节因子
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human Smad3 around the phosphorylation site of Ser423
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
b-FABP(Human brain fatty acid binding protein) ELISA Kit 人脑型脂肪酸结合蛋白 Multi-class antibodies
BK(Human Bradykinin) ELISA Kit 人血管舒缓激肽 Multi-class antibodies
MLC(Human Myosin light Chain) ELISA Kit 人肌球蛋白轻链 Multi-class antibodies
ACTN-3(Human Alpha-Actinin 3) ELISA Kit 人α-辅肌动蛋白3 Multi-class antibodies
hs-CRP(Human high sensitivity C-Reactive Protein) ELISA Kit 人超敏C反应蛋白 Multi-class antibodies
Tn- I (Human Troponin I ) ELISA Kit 人肌钙蛋白Ⅰ Multi-class antibodies
SAA(Human Serum amyloid A) ELISA Kit 人血清淀粉样蛋白A Multi-class antibodies
Hsp-60(Human Heat Shock Protein 60) ELISA Kit 人热休克蛋白60 Multi-class antibodies
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
磷酸化细胞信号转导分子SMAD3抗体保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Smad3 is a 50 kDa member of a family of proteins that act as key mediators of TGF beta superfamily signaling in cell proliferation, differentiation and development. The Smad family is divided into three subclasses: receptor regulated Smads, activin/TGF beta receptor regulated (Smad2 and 3) or BMP receptor regulated (Smad 1, 5, and 8); the common partner, (Smad4) that functions via its interaction to the various Smads; and the inhibitory Smads, (Smad6 and 7). Activated Smad3 oligomerizes with Smad4 upon TGF beta stimulation and translocates as a complex into the nucleus, allowing its binding to DNA and transcription factors. Phosphorylation of the two TGF beta dependent serines 423 and 425 in the C terminus of Smad3 is critical for Smad3 transcriptional activity and TGF beta signaling.
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