神经特异蛋白酪氨酸磷酸酶N5抗体

神经特异蛋白酪氨酸磷酸酶N5抗体形态：液态

抗体纯度： >95% By SDS-PAGE

保存环境：2-8℃ 短期保存或<-20℃长期保存保存 1 年以上，避免反复冻融。    

神经特异蛋白酪氨酸磷酸酶N5抗体英文名称  Anti-PTPN5/STEP

中文名称  神经特异蛋白酪氨酸磷酸酶N5抗体

别    名  Neural specific protein tyrosine phosphatase; Neural-specific protein-tyrosine phosphatase; Protein tyrosine phosphatase non receptor type 5 (striatum enriched); Protein tyrosine phosphatase non receptor type 5; Protein tyrosine phosphatase striatum enriched; PTN5; PTN5_HUMAN; PTP STEP; PTPN 5; Ptpn5; PTPSTEP; STEP; Striatum-enriched protein-tyrosine phosphatase; Tyrosine protein phosphatase non receptor type 5; Tyrosine-protein phosphatase non-receptor type 5; FLJ14427.

我们提供抗体来源有人、小鼠、大鼠、兔等动物，规格多样，全国免邮，我们用更安全的方式方法保存及运输神经特异蛋白酪氨酸磷酸酶N5抗体。

本公司专业供应各种进口、国产一抗及二抗，品牌有R&D、Santa Cruz、Bipec、Millipore等国际知名品牌，品种多达7000多种，由于产品的数量众多，产品的宿主、抗原来源及应用范围(WB、IH(F/P)、FC、ELISA、IP、IF等)有所不同。

我们还可以为客户提供BAP31蛋白抗体的纯化和标记服务，具体包括盐析沉淀纯化、Portein A/G纯化、免疫亲和纯化、HRP标记、FITC标记等。

神经特异蛋白酪氨酸磷酸酶N5抗体的详细介绍：

浓    度  1mg/1ml 

规 格  0.2ml/200μg 

抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat, Rabbit,   

产品类型  一抗    

研究领域  细胞生物 神经生物学 信号转导 激酶和磷酸酶  

蛋白分子量  predicted molecular weight: 63kDa 

性    状  Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human PTPN5

亚    型  IgG

纯化方法  affinity purified by Protein A

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0

Alpha casein  α酪蛋白抗体 0.2ml

Alpha s1 Casein  α-s1酪蛋白抗体 0.2ml

Alpha s2 Casein  α-s2酪蛋白抗体 0.2ml

Alpha-Catenin/CTNNA1  α-连环蛋白抗体（钙粘蛋白相关蛋白） 0.1ml

Alpha-ENaC  钠通道蛋白α ENaC 0.2ml

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500

（石蜡切片需做抗原修复）

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

神经特异蛋白酪氨酸磷酸酶N5抗体产品介绍 The brain-specific STEP (striatal enriched phosphatase) family of protein tyrosine phosphatases (PTPs) comprises both transmembrane and cytosolic protein members which are the products of alternative splicing. STEP family members are expressed in the dopaminoceptive neurons of the CNS, with highest expression in the basal ganglia and related structures. The STEP protein regulates the N-methyl-d-aspartate receptor (NMDAR) complex; STEP depresses both NMDAR single-channel activity and synaptic currents. The membrane-associated STEP61 isoform localizes in the postsynaptic densities (PSDs) of striatal neurons. STEP61 contains a single tyrosine phosphatase domain, two proline-rich domains and two transmembrane domains. The STEP61 protein associates with the Src family kinase member Fyn when Fyn is phosphorylated at Tyr-420 and not Tyr-431. Upon association, STEP61 dephosphorylates Tyr-420 residue and may thus regulate Fyn activity in PSDs. Isolated from mouse brain, the STEP20 isoform lacks the conserved tyrosine phosphatase domain. The human STEP gene maps to chromosome 11p15.2-p15.1.