细胞毒性受体NK-p46抗体

细胞毒性受体NK-p46抗体

产品标准

 浓缩液(1mg/1ml) 亲和纯化抗体

细胞毒性受体NK-p46抗体产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

细胞毒性受体NK-p46抗体产品介绍

    NKp46是很重要的的自然细胞毒受体，在自然杀伤作用中起关键作用。细胞毒性受体家族（NCRs）主要有：NKp46、NKp44和NKp30，其中NKp46和NKp30表达于所有静止和活化的NK细胞，而NKp44则选择性的表达于活化的NK细胞。靶细胞上的配体分子与NCRs的结合（交联）引发NK细胞的活化导致靶细胞的裂解和大量细胞因子的产生。现已确认NKp46和NKp44可以识别病毒上的配体分子红血球凝聚素，而NKp46则能识别肿瘤细胞上的乙酰硫酸多聚糖。
    The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NCR1 is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 amino acid residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NCR1 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. NCR1 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.
    mol wt:33/36kDa(human/mo, rat) 
    Other Aliases: 
    Natural killer cell p46-related protein; Natural cytotoxicity triggering receptor 1; NK-p46; NKp46; NK cell-activating receptor; Lymphocyte antigen 94 homolog; CD335; NCR1; LY94

xy-15417R HBLD2铁硫簇整合同源物2蛋白抗体

xy-0887R MV hemagglutinin glycoprotein麻疹病毒血凝素抗体

xy-11589R HOXC5同源盒蛋白HOXC5抗体

xy-11567R HES4转录因子HES4抗体

xy-11568R HS1BP3造血干细胞特异性相关结合蛋白3抗体

细胞毒性受体NK-p46抗体

xy-8316R HDHD1HDHD1蛋白抗体

xy-8317R HDHD2HDHD2蛋白抗体

xy-7803R HCF-1宿主细胞因子1抗体

xy-7749R HIST1H2AH组蛋白H2A/S抗体

xy-6664R HRH2组胺受体H2抗体

xy-6665R phospho-HRH1(Ser398)磷酸化组胺受体H1抗体

xy-6666R HOXA11同源盒蛋白HOXA11抗体

xy-6663R HRH1组胺受体H1抗体

xy-6667R HOXA9同源盒蛋白HOXA9抗体

xy-6668R HOXB5同源盒蛋白HOXB5抗体

xy-5840R HEPACAM肝细胞粘附分子抗体

xy-10326R Phospho-HDAC5 (Ser259)磷酸化组蛋白去乙酰化酶5抗体

xy-5388R phospho-HDAC1 (Ser423+Ser421) 磷酸化组蛋白去乙酰化酶1抗体

xy-5389R phospho-HDAC2 (Ser394)磷酸化组蛋白去乙酰化酶2抗体

xy-5392R phospho-HOMER3 (Thr36)磷酸化HOMER3蛋白抗体

xy-6165R HRAS+KRAS转化蛋白p21抗体（原癌基因H-ras抗体）

xy-2972R HES1转录因子HES-1抗体

xy-6191R H3-K4-HMTase SETD7组蛋白H4-K4甲基转移酶抗体

xy-5391R HOMER3HOMER3蛋白抗体

xy-5340R Phospho-HER3(Tyr1328)磷酸化HER3受体抗体

xy-5342R Phospho-HER4 (Tyr1162)磷酸化HER4抗体

xy-5343R Phospho-HER4 (Tyr1188)磷酸化HER4抗体

xy-3905R HSD17B3羟类固醇脱氢酶17β3抗体

xy-3904R HSD11B1羟基类固醇脱氢酶11β1抗体

xy-3906R HSD3B1滋养层细胞抗原3β-HSD抗体

xy-4016R Acetyl-Histone H4(K8)乙酰化组蛋白H4抗体

xy-5384R phospho-HMGN1(Ser20+Ser24)磷酸化高迁移率核小体结合蛋白1

xy-4838R HE4附睾分泌蛋白4抗体

xy-4715R Histone H3 (Tri Methyl K4)三甲基化组蛋白H3抗体

xy-5068R HMGCR三羟基三甲基辅酶A还原酶抗体

xy-5072R Heparan Sulfate Proteoglycan 2硫酸乙酰肝素蛋白多糖2

xy-15421R HCA25a肝癌相关抗原hca25a