产品详情

山奈酚

97%

Product Name: Kaempferol

别名:	山奈酚 ;莰菲醇，3,4',5,7-四羟基黄酮
CAS号:	520-18-3
分子式:	C₁₅H₁₀O₆
分子量:	286.24
MDL号:	MFCD00016938

山奈酚

用途:	一种黄酮醇。能使佛波醇酯处理的小鼠成纤维细胞或v-H-ras-转化的 NIH 3T3细胞变形后的恢复。能显著诱导核DNA退化，同时伴随脂类的过氧化反应。抑制拓扑异构酶I催化的DNA再连接。
熔点:	276℃
特定比重:	1.688
贮存:	储存温度 -20°C
生化和生理学机理:	Description： IC50 value: Kaempferol inhibits proliferation of ovarian cancer cells at 40μM or higher concentrations[2]. Kaempferol (3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one) is a relatively common nontoxic, natural dietary compound which has been reported to reduce the risk of ovarian cancer[1]. in vitro: Kaempferol was found to inhibit estrogen receptor alpha expression in breast cancer cells and to induce apoptosis in glioblastoma cells and lung cancer cells by activation of MEK-MAPK. Studies have shown that kaempferol also has anti-inflammatory effects via inhibition of interleukin-4 and cyclo-oxygenase 2 expression by suppressing Src kinase and downregulating the NFκB pathway. Kaempferol is also effective in inhibiting angiogenesis and inducing apoptosis in ovarian cancer cells [1]. kaempferol has a distinct epigenetic activity by inhibition of histone deacetylases (HDACs). In silico docking analysis revealed that it fits into the binding pocket of HDAC2, 4, 7 or 8 and thereby binds to the zinc ion of the catalytic center. Further in vitro profiling of all conserved human HDACs of class I, II and IV showed that kaempferol inhibited all tested HDACs [4]. in vivo: Male BALB/c mice with ALI, induced by intranasal instillation of LPS, were treated or not with Kae (100 mg/kg, intragastrically) 1h prior to LPS exposure. Kae treatment attenuated pulmonary edema of mice with ALI after LPS challenge, as it markedly decreased the lung W/D ratio of lung samples, protein concentration and the amounts of inflammatory cells in BALF[3]. Clinical trial:N/A

山奈酚

S0168氨基磺酸铵/氨磺酸铵/磺酸一铵盐/AMSAR，99%

S01692,4,6-三溴-3-羟基苯甲酸/3-羟基-2,4,6-三溴苯甲酸/TBHBABR，98%

S0170氨三乙酸/氨基三乙酸/氮三乙酸/N,N-双(羧甲基)甘氨酸/三(羧甲基)胺/三甘氨酸/α,α′,α″-三甲基胺三羧酸/氨羧络合剂I/络合剂I/托立龙A/特里隆A/氮川三乙酸/次氮基三乙酸/次氨基三乙酸/N,N-二(羧甲基)甘氨酸/氮基三乙酸/氮川三乙酸氨羧络合剂I /NTAAR，98.5%

S0171氯化血红素/血晶素/血红素/卟啉铁/血晶/盐酸血红素/氯高铁血红素/氯化高铁血红素/Hematin chlorideBR，98%

S01724-氯-1-萘酚/4-氯-α-萘酚/氯萘酚/4C1N/4-CN超纯，99%

S01731-萘酚/1-羟基萘/甲萘酚/α-萘酚/α-羟基萘/1-NaphtyolAR，99%

S01742-萘酚/二萘酚/乙萘酚/异萘酚/β-萘酚/β-羟基萘/2-羟基萘/2-NaphtholAR，99%

S0175邻苯二酚/儿茶酚/焦性儿茶酚/1,2-二羟基苯/1,2-苯二酚/邻苯二酚/焦儿茶酚/PyrocatecholCP，98%

S0176乙二醛缩双（邻氨基酚）/乙二醛缩双邻羟苯胺/乙二醛双(2-羟基苯胺)/钙红/乙二醛缩双(邻氨基苯酚)/乙二醛-双(2-羟基缩苯胺)/新钙试剂/GBHACP

S01774-(4-硝基苯偶氮)-1-萘酚/4-(对硝基苯偶氮)-1-萘酚/对硝基偶氮苯-α-萘酚/镁试剂II/4-硝基苯-(1-偶氮-1)-4-羟基萘/4-[(4-硝基苯基)偶氮]-1-萘酚/对硝基苯偶氮-1-萘酚/4-(4-氨苯酚)-1-萘酚/4-(4-Nitrophenylazo)-1-naphtholAR

S0178茚三酮/苯并戊三酮/水合茚三酮/苯骈戊三酮/苯并环丙三酮/2,2-二羟基-1H-茚并-1,3(2H)-二酮/水合三酮氢茚/宁海群/NinhydrinAR，95%

S0179蒽酮/9,10-二氢-9-氧蒽/9(10H)-蒽酮/恩酮/9,10-二氫蒽-9-酮/AnthroneAR

S0180四丁基硫酸氢铵/硫酸氢四丁铵/四丁基硫氢酸铵/正四丁基硫酸氢基铵/四丁基酒石酸氢铵/硫酸氢化四丁基/TBAHS/IPC-TBA-HSAR，98%色谱级，99%

S01814，4-双（二甲氨基）硫代二苯甲酮/4,4-双(二甲氨基)硫代二甲酮/硫代米氏酮/4,4′-四甲基二氨基硫代二苯甲酮/对,对′-四甲基二氨基二苯硫酮/4,4′-双(二甲氨基)硫代二苯甲酮/4,4'-双二甲氨基硫代二苯甲酮/硫代米蚩酮/双[4-(二甲氨基)苯基]甲硫酮/4,4'-双(二甲胺基)硫代苯甲酮/Thiomichler's ketoneAR，97%

S0182米氏酮/4，4′-四甲基二氨基二苯甲酮/米蚩酮/米气勒氏酮/四甲对，对′-二氨二苯甲酮/4,4′-双(二甲氨基)二苯酮/四甲基米氏酮/4,4'-二(N,N-二甲氨基)二苯甲酮/4,4’-二(N,N-二甲氨基)二苯酮/4,4’-双(二甲氨基)二苯甲酮/双二甲氨基苯甲酮/4,4′-双(二甲氨基)苯甲酮/Michler's ketoneCP，98%

S0183苯芴酮/锗试剂/苯基芴酮/苯基荧光酮/2,6,7-三羟基-9-苯基荧光酮/2,6,7-三羟基-9-苯基-3H-呫吨-3-酮/9-苯基-2,3,7-三羟基-6-氧蒽酮/2,6,7-三羟基-9-苯基-6-荧光酮/9-苯基-2,3,7-三羟基-6-荧光酮/PhenylfluoroneAR

S01841-苯基-3-甲基-4-苯甲酰基吡唑啉酮/1-苯基-3-甲基-4-苯甲酰基-5-吡唑啉酮/4-苯甲酰基-3-甲基-1-苯基-2-吡唑啉-5-酮/萃取剂II/4-苯甲酰-3-甲基-1-苯基-5-吡唑啉酮/4-苯甲酰基-3-甲基-1-苯基-2-吡唑-5-酮/HPMBP/PMBPAR

S01851-苯基-3-甲基-5-吡唑酮/依达拉奉/3-甲基-1-苯基-2-吡唑啉-5-酮/3-甲基-1-苯基-5-吡唑啉酮/1,3,5-吡唑酮/1-苯基-3-甲基-5-吡唑啉酮/苯基甲基氮茂-5-酮/2,4-二氢-5-甲基-2-苯基-3H-吡唑-3-酮/PMPAR，99%

S01861-苯基-3-吡唑烷酮/菲尼酮/菲尼酮A/3-甲基-1-苯基-吡唑啉-5-酮/1,3,5-吡唑酮/3-甲基-1-苯基-2-吡唑啉-5-酮/1-苯基-3-吡唑啉酮/1-苯基-3-氧-1,2-二氮杂茂/1-苯基-3-吡唑酮/1-苯-3-吡唑啉酮/PhenidoneCP

S0187α-萘酚苯甲醇/α-纳富妥苯/4-[(4-羟基-1-萘基)苯基亚甲基]-1(4H)-萘酮/α-对萘酚苯/对萘酚苯甲醇/4,4’-(α-羟基亚苄基)二(1-萘酚)/α-萘酚基萘酚醌基苯甲烷/α-萘酚醌苯基甲烷/α-萘酚醌烷/α-萘酚苯/1-萘酚苯/α-NaphtholbenzeinBR，90%

S0188偶氮胭脂红B/偶氮洋红B/偶氮红B/Azocarmine BBS

S0189偶氮胭脂红G/酸性红101/偶氮洋红G/玫红对氮蒽/偶氮红G/罗星杜林/玫红杜林/Azocarmine GBS

S0190硫堇/劳氏青莲/劳氏紫/氯化-3,7-二氨基吩噻嗪/7-氨基-3-亚氨基-3H-苯并噻嗪氯化氢/3,7-二氨基吩噻嗪-5-翁氯化物/硫槿/氯化劳氏紫/ThioninBR

S0191酒石黄/肼黄/食用柠檬黄/酸性黄23/1-(4-磺酸苯基)-4-(4-磺酸苯基偶氮)-5-吡唑啉酮-3-羧酸三钠盐/食用色素黄色5号/他特秦/ TartrazineBS，85%

S0192诱惑红/6-羟基-5-［(2-甲氧基-5-甲基-4-磺本基)偶氮］2-萘磺酸二钠盐/诱惑红AC/食品红17/大红贝司RC/显色基艳红RB/咖喱红/红 40 [CI 16035]/C.I.冰染重氮组分13/Allura Red ACAR，85%

S0193日落黄/日落黄FCF/1-对磺酸苯基偶氮-2-羟基萘-6-磺酸二钠盐/食用黄色6号/食品黄3/食用桔黄/Sunset Yellow FCFAR，87%

S0194丽丝胺罗丹明B/酸性罗丹明B/酸性红52/二甲苯红B/丽丝胺玫瑰红B/里斯沙明玫瑰红B200/李斯曼罗丹明B/李斯曼若丹明B/丽丝胺碱性蕊香红B200/酸性玫瑰红B/酸性桃红B/柴林红B/磺化罗丹明B/奇通红S/硫罗丹明B /Lissamine rhodamine BBS高纯，75%

S0195酚番红花红/酚藏红花/酚藏花红/3,7-二氨基-5-苯基吩嗪翁氯化物/奎诺二甲基酯/PhenosafranineIND

S0196磺酰罗丹明B/磺酰罗丹明B细胞培养试剂染料/硫丹明B/Sulforhodamine B激光级，95%

S0197依来铬氰蓝R/蓝光酸性铬花青/羊毛铬菁/媒介蓝3/羊毛铬花青R/3,3'-(3H-2,1-苯并恶噻-3-亚基)双(6-羟基-5-甲基苯甲酸) S,S-二氧化物三钠盐/铬花青R /Eriochrome cyanine R试剂级

S0198茜素蓝S/Alizarin blue S色固

供货周期：	现货
品牌：	AMRESCO
型号：	g/mg
货号：	XY-107145