供货周期: | 现货 |
品牌: | AMRESCO |
规格: | g/mg |
货号: | XY-110731 |
CAS号: |
Product Name: 5-Bromo-2′-deoxyuridine
别名: | 5-溴-2'-脱氧尿苷;5'-溴尿嘧啶核苷;溴脲苷;5-溴-1-(2-脱氧-β-D-呋喃核糖)尿嘧啶;5-溴脱氧尿苷;5-溴去氧脲苷;5-BrdU |
CAS号: | 59-14-3 |
分子式: | C9H11BrN2O5 |
分子量: | 307.10 |
EINECS编号: | 200-415-9 |
MDL号: | MFCD00006529 |
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介绍: | 5-Bromo-2'-deoxyuridine is a thymidine analog. Useful for the study of DNA synthesis where it is incorporated into DNA in place of thymidine. 5-Bromo-2'-deoxyuridine can be used to label DNA. The resulting DNA can be used in conjunction with BrdU Monoclonal Antibody for the immunohistochemical analysis of cell proliferation. |
用途: | 胸腺嘧啶类似物,在遗传学研究中用作诱变剂(mutagen),在细胞分裂的S-期选择性地插进DNA。 |
熔点: | 191-194℃ |
特定比重: | 1.905 |
比旋光度: | 22 ° (C=1, H2O) |
贮存: | -20℃保存 |
敏感性: | 对空气敏感 |
可溶性: | Soluble in water (10 mg/mL), NH4OH (0.1 M) at 20 °C, DMF, DMSO, and sodium hydroxide. |
生化和生理学机理: | 5-Bromo-2′-deoxyuridine (5-BrdU) is a thymidine analogue which is incorporated into DNA. 5-BrdU is routinely and extensively used to measure DNA synthesis and to label dividing cells. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation. |
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