供货周期: | 现货 |
品牌: | TRC |
规格: | 5mg |
货号: | R124000 |
CAS号: | 53123-88-9 |
Chemical Name: Rapamycin
Catalogue Number: R124000
Synonyms: (-)-Rapamycin; AY 22989; Antibiotic AY 22989; Cypher; NSC 226080; RAPA; RPM; Rapammune; Rapamune; SIIA 9268A; Sirolimus; Wy 090217;
CAS Number: 53123-88-9
Possible CAS Number: NA
Mol. Formula: C51H79NO13
Appearance: White to Off-White Solid
Melting Point: 183-185°C
Mol. Weight: 914.17
Storage: -20°C Freezer
Stability: No Data Available
Solubility: Chloroform, Methanol
Boiling Point: No Data Available
Category: Chiral Reagents, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Applications: A triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants.
References: Martel, P.R., et al.: Can. J. Physiol. Pharmacol., 55, 48 (1977), Carlson, R.P., et al.: J. Pharmacol. Exp. Ther., 266, 1125 (1993), Kahan, B.D., et al.: Lancet, 356, 194 (2000), Holmes, D.R., et al.: Circulation, 109, 634 (2004),
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