联会复合体蛋白3抗体elisa实验

英文名称  Anti-SCP3 

中文名称  联会复合体蛋白3抗体 

联会复合体蛋白3抗体别    名  COR 1; COR1; MGC71888; RNASCP3; SCP 3; Sycp 3; Sycp3; Synaptonemal complex protein 3; CTDSL_HUMAN; CTD small phosphatase-like protein; CTDSP-like; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3; NIF-like protein; Nuclear LIM interactor-interacting factor 1; NLI-interacting factor 1; AltName: Full=Protein YA22; hYA22; RBSP3; AltName: Full=Small C-terminal domain phosphatase 3; SCP3; Small CTD phosphatase 3. 

浓    度  1mg/1ml 

规 格  0.1ml/100μg  0.2ml/200μg 

抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit  

产品类型  一抗    

研究领域  细胞生物 免疫学 发育生物学 细胞周期蛋白  

蛋白分子量  predicted molecular weight: 31kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human SCP3 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide 

联会复合体蛋白3抗体产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 During meiosis, the homologous chromosomes pair and recombine, a process essential for generating genetically distinct haploid cells. The unique behavior displayed by meiotic chromosomes has been linked to the activities of a meiosis-specific supramolecular proteinaceous structure, the synaptonemal complex (SC). Three meiosis-specific components of the SC have been characterized in mammals, SCP1, SCP2 and SCP3. SCP3 has a C-terminal coiled-coil domain that has been shown to promote homotypic interactions in vitro.

Function : Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.

Subunit : Monomer. Interacts with REST.

Subcellular Location : Nucleus (By similarity).

Tissue Specificity : Expression is restricted to non-neuronal tissues.

联会复合体蛋白3抗体Similarity : Contains 1 FCP1 homology domain.

Database links : UniProtKB/Swiss-Prot: O15194.2