三号染色体开放阅读框抗体

英文名称  Anti-APRG1/C3orf35 

中文名称  三号染色体开放阅读框抗体 

三号染色体开放阅读框抗体别    名  AP20 region protein 1; APRG1; APRG1_HUMAN; C3orf35; chromosome 3 open reading frame 35. 

浓    度  1mg/1ml 

规 格  0.2ml/200μg   

抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human   

产品类型  一抗    

研究领域  肿瘤 细胞生物 细胞膜蛋白  

蛋白分子量  predicted molecular weight: 19kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human APRG1/C3orf35 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 

产品应用   ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

三号染色体开放阅读框抗体保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 APRG1 is a 170 amino acid single-pass membrane protein that exists as 3 alternatively spliced isoforms. APRG1 isoform 1 is highly expressed in placenta and pancreas, while isoform 2 is mainly expressed in kidney. The gene encoding APRG1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated 三号染色体开放阅读框抗体with chromosome 3.

Subcellular Location : Membrane; Single-pass membrane protein (Potential). 

Tissue Specificity : Isoform 1 is expressed at high levels in the pancreas and placenta. Isoform 2 is expressed at high levels in the kidney.

Database links : UniProtKB/Swiss-Prot: Q8IVJ8.2