锌指蛋白851抗体

英文名称  Anti-ZNF851/BTBD15/ZBTB44 

中文名称  锌指蛋白851抗体 

锌指蛋白851抗体别    名  BTB (POZ) domain containing 15; BTB/POZ domain-containing protein 15; BTBD15; HSPC063; MGC26123; MGC57431; MGC60348; MGC88058; OTTHUMP00000230934; OTTHUMP00000230935; OTTHUMP00000230937; OTTHUMP00000230938; ZBT44_HUMAN; Zbtb44; Zinc finger and BTB domain containing 44; Zinc finger and BTB domain-containing protein 44; Zinc finger protein 851; ZNF851. 

浓    度  1mg/1ml 

规 格  0.2ml/200μg 

抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep  

产品类型  一抗    

研究领域  肿瘤 细胞生物 转录调节因子 表观遗传学  

蛋白分子量  predicted molecular weight: 64kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human ZBTB44 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

锌指蛋白851抗体保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying protein. ZBTB44 is a 570 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB44 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB44 functions as a transcription regulator. Four isoforms of ZBTB44 have been identified.

锌指蛋白851抗体Function : May be involved in transcriptional regulation.

Subcellular Location : Nucleus.

Post-translational modifications : modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.

Similarity : Contains 1 BTB (POZ) domain.

Contains 4 C2H2-type zinc fingers.

Database links : UniProtKB/Swiss-Prot: Q8NCP5.1