STAC1蛋白抗体

英文名称  Anti-STAC 

中文名称  STAC1蛋白抗体 

STAC1蛋白抗体别    名  SH3 and cysteine rich domain; SH3 and cysteine rich domain containing protein; SRC homology 3 and cysteine rich domain protein; Src homology three (SH3) and cysteine rich domain; STAC 1; STAC1; STAC-1; FLJ32331; STAC_HUMAN. 

浓    度  1mg/1ml 

规 格  0.2ml/200μg   

抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep

产品类型  一抗    

研究领域  神经生物学 信号转导  

蛋白分子量  predicted molecular weight: 45kDa 

STAC1蛋白抗体性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human STAC (11-100aa) 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

STAC1蛋白抗体产品介绍 STAC (SH3 and cysteine rich domain-containing protein), also known as STAC1, is a 402 amino acid protein that contains one SH3 (Src homology 3) domain and one cysteine-rich domain (CRD). Expressed in brain, STAC is a neuron-specific protein that localizes to the cytoplasm and, based on the frequent involvement of SH3 and CRD domains in signal transduction, is believed to play a role in neuron-specific signal transduction. In addition, STAC may be involved in protecting cells from apoptosis. Due to its neuron-specific expression and putative role in signal transduction, STAC may be implicated in a variety of hereditary neurological diseases.

Function : STAC is a neuron-specific protein, expressed predominantly in the hippocampus, cerebellum and inferior olive. It contains a cysteine-rich domain and an SH3 domain. These domains are frequently found in signal transduction proteins suggesting that STAC may be involved in neuron-specific signal transduction. 

Subcellular Location : Cytoplasmic

Similarity : Contains 1 phorbol-ester/DAG-type zinc finger.

Contains 1 SH3 domain. 

Database links : UniProtKB/Swiss-Prot: Q99469.1