生长分化因子8/肌肉抑制素抗体elisa实验|0.1ml/100μg 0.2ml/200μg|BJ-0220-上海邦景实业有限公司

生长分化因子8/肌肉抑制素抗体elisa实验

参考价：面议

供货周期：

现货

品牌：

GenWay

规格：

0.1ml/100μg 0.2ml/200μg

货号：

BJ-0220

CAS号：

产品详情

英文名称 Anti-GDF8

中文名称 生长分化因子8/肌肉抑制素抗体

别名 MSTN; growth differntiation factor 8; GDF 8; Growth differentiation factor 8; Growth/Differentiation Factor 8; myostatin.

浓度 1mg/1ml

规格 0.2ml/200μg

生长分化因子8/肌肉抑制素抗体抗体来源 Goat

克隆类型 polyclonal

交叉反应 Human, Mouse, Rat, Dog, Pig, Cow

产品类型一抗

研究领域免疫学生长因子和激素细胞分化

蛋白分子量 predicted molecular weight: 12/43kDa

性状 Lyophilized or Liquid

免疫原 Recombinant fusion protein, His tagged

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

生长分化因子8/肌肉抑制素抗体产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 Myostatin (GDF8)is expressed uniquely in human skeletal muscle as a 12 kDa mature glycoprotein consisting of 113 amino acid residues and secreted into plasma. Myostatin is a member of the transforming growth factor beta superfamily of secreted growth and differentiation factors that is essential for proper regulation of skeletal muscle mass. Studies have shown that myostatin could play an important role in cardiac development and physiology.

Subunit : Homodimer; disulfide-linked.

Subcellular Location : Secreted.

Tissue Specificity : Predominantly expressed in muscle. At hatching, expression is strongest in the skin epithelium, and is also found in the retina and brain. From day 28, expressed in skeletal muscle. In the adult, highest expression is seen in the gastrointestinal tract, brain, muscle, heart and testis. Also expressed in the adult pharynx, kidney, spleen, liver, gill, eyes, skin, swim bladder and ovary.

生长分化因子8/肌肉抑制素抗体Similarity : Belongs to the TGF-beta family.

GDF-8又称MSTN,是转化生长因子超家族，也是近年来发现的一类重要的肌细胞生长调控因子，它通过抑制MyoD家族成员转录活性负向控制肌细胞的生长发育，它的表达量与肌肉重量的变化呈负相关。

行业应用

细胞球蛋白生物学检测

医疗/卫生 2016/03/17