B脑蛋白44抗体elisa实验|0.1ml/100μg 0.2ml/200μg|BJ-3763-上海邦景实业有限公司

B脑蛋白44抗体elisa实验

参考价：面议

供货周期：

现货

品牌：

GenWay

规格：

0.1ml/100μg 0.2ml/200μg

货号：

BJ-3763

CAS号：

产品详情

脑蛋白44抗体英文名称 Anti-BRP44

中文名称 脑蛋白44抗体

别名 ESTM43; MGC125753; BR44_HUMAN; Brain protein 44; BRP44; DKFZp564B167; MGC125752; rCG_46381; RGD1563422; RP1-295C6.1.

浓度 1mg/1ml

规格 0.2ml/200μg

脑蛋白44抗体抗体来源 Rabbit

克隆类型 polyclonal

交叉反应 Human, Mouse, Rat

产品类型一抗

研究领域肿瘤细胞生物免疫学神经生物学

蛋白分子量 predicted molecular weight: 14kDa

性状 Lyophilized or Liquid

免疫原 KLH conjugated synthetic peptide derived from human BRP44

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 BRP44 is a 127 amino acid protein belonging to the UPF0041 family. The gene that encodes BRP44 maps to human chromosome 1, which is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

脑蛋白44抗体Function : Mediates the uptake of pyruvate into mitochondria.

Subunit : The functional 150 kDa pyruvate import complex is a heteromer of MPC1 and MPC2 (By similarity).

Subcellular Location : Mitochondrion inner membrane; Multi-pass membrane protein.

Similarity : Belongs to the mitochondrial pyruvate carrier (MPC) family.

Database links : UniProtKB/Swiss-Prot: O95563.1