供货周期: | 现货 |
品牌: | GenWay |
规格: | 0.1ml/100μg 0.2ml/200μg |
货号: | BJ-3809 |
CAS号: |
乳腺癌相关蛋白1抗体英文名称 Anti-BIN2/BRAP1
中文名称 乳腺癌相关蛋白1抗体
别 名 BIN2; BIN2_HUMAN; BRAP 1; Breast cancer associated protein BRAP1; Breast cancer-associated protein 1; Bridging integrator 2.
浓 度 1mg/1ml
规 格 0.2ml/200μg
乳腺癌相关蛋白1抗体抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep
产品类型 一抗
研究领域 肿瘤 细胞生物 免疫学
蛋白分子量 predicted molecular weight: 62kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human BIN2/BRAP1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 BAR proteins are characterized by a common N-terminal BAR (bin, amphiphysin and Rvs161/167) domain and are recognized as adaptor proteins that are involved in many cellular processes. BIN1 and BIN2 are BAR proteins that share 61% sequence similarity. BIN1 (Bridging integrator 1) is a ubiquitously expressed regulatory protein for synaptic vesicle endocytosis. BIN1 also interacts with the transcription factors c-Myc and MyoD, potentially functioning as a tumor suppressor. BIN2, also known as Breast cancer-associated protein 1, is a 565 amino acid protein that interacts with BIN1. In contrast to BIN1, BIN2 lacks tumor suppressor features as well as a c-Myc interacting region. BIN2 shows preferred expression in tissues of hematopoietic origin, with high levels found in spleen, thymus, colon, placenta, lymphoid and granulocytic cells. There are two isoforms of BIN2 that are produced as a result of alternative splicing events.
乳腺癌相关蛋白1抗体Subunit : Interacts with BIN1.
Subcellular Location : Cytoplasm.
Tissue Specificity : Highest level expression seen in spleen and peripheral blood leukocytes and is also expressed at high levels in thymus, colon and placenta, suggesting preferential expression in hematopoietic tissues.
Similarity : Contains 1 BAR domain.
Database links : UniProtKB/Swiss-Prot: Q9UBW5.3
相关产品
6号染色体开放阅读框72抗体elisa实验
6号染色体开放阅读框70抗体elisa实验
6号染色体开放阅读框62抗体elisa实验
6号染色体开放阅读框58抗体elisa实验
6号染色体开放阅读框57抗体elisa实验
6号染色体开放阅读框52抗体elisa实验
6号染色体开放阅读框35抗体elisa实验
6号染色体开放阅读框25抗体elisa实验
6号染色体开放阅读框225抗体elisa实验
6号染色体开放阅读框211抗体elisa实验
6号染色体开放阅读框206抗体elisa实验
6号染色体开放阅读框204抗体elisa实验
6号染色体开放阅读框203抗体elisa实验
6号染色体开放阅读框201抗体elisa实验
6号染色体开放阅读框199抗体elisa实验
详细地址
关注
拨打电话
留言咨询