7号染色体开放阅读框27抗体elisa实验|0.1ml/100μg 0.2ml/200μg|BJ-3821-上海邦景实业有限公司

7号染色体开放阅读框27抗体elisa实验

参考价：面议

供货周期：

现货

品牌：

GenWay

规格：

0.1ml/100μg 0.2ml/200μg

货号：

BJ-3821

CAS号：

产品详情

7号染色体开放阅读框27抗体英文名称 Anti-BAAT1/C7orf27

中文名称 7号染色体开放阅读框27抗体

别名 BAAT 1; BAAT1; BRAT-1; brat1; BRAT1_HUMAN; BRCA1-associated ATM activator 1; BRCA1-associated protein required for ATM activation protein 1; BRCA1-associated protein required for ATM activation-1; C7orf27; chromosome 7 open reading frame 27; HEAT repeat containing protein C7orf27.

浓度 1mg/1ml

7号染色体开放阅读框27抗体规格 0.2ml/200μg

抗体来源 Rabbit

克隆类型 polyclonal

交叉反应 Human, Mouse, Rat

产品类型一抗

研究领域细胞生物免疫学

蛋白分子量 predicted molecular weight: 88kDa

性状 Lyophilized or Liquid

免疫原 KLH conjugated synthetic peptide derived from human BAAT1/C7orf27

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍

Function : Required for activation of ATM following ionizing radiation. May act by regulating dephosphorylation of ATM.

Subunit : Interacts with BRCA1 and ATM.

Subcellular Location : Nucleus. Present at double strand breaks (DSBs) following ionizing radiation treatment.

Tissue Specificity : Ubiquitously expressed.

Post-translational modifications :

DISEASE : Defects in BRAT1 are the cause of rigidity and multifocal seizure syndrome, lethal neonatal (RMFSL) [MIM:614498]. A lethal, neonatal, neurologic disorder characterized by episodic jerking that is apparent in utero, lack of 7号染色体开放阅读框27抗体psychomotor development, axial and limb rigidity, frequent multifocal seizures, and dysautonomia. At birth, affected individuals have small heads, overlapping cranial sutures, small or absent fontanels, and depressed frontal bones. Infants show poorly responsive focal jerks of the tongue, face and arms in a nearly continuous sequence throughout life.

Similarity : Contains 2 HEAT repeats.

Database links : UniProtKB/Swiss-Prot: Q6PJG6.2