缓激肽B1受体抗体elisa实验|0.1ml/100μg 0.2ml/200μg|BJ-3823-上海邦景实业有限公司

缓激肽B1受体抗体elisa实验

参考价：面议

供货周期：

现货

品牌：

GenWay

规格：

0.1ml/100μg 0.2ml/200μg

货号：

BJ-3823

CAS号：

产品详情

缓激肽B1受体抗体英文名称 Anti-BDKRB1

中文名称 缓激肽B1受体抗体

别名 B1 bradykinin receptor; B1BKR; B1R; BDKR B1; BDKRB 1; BDKRB1; BK 1 receptor; BK-1 receptor; bradykinin B1 R; BKB1R; BKR 1; BKR1; BKRB1_HUMAN; BRADY B1; BRADYB1; Bradykinin B1 receptor; Bradykinin receptor 1; bradykinin B1R; Bradykinin receptor B1

浓度 1mg/1ml

缓激肽B1受体抗体规格 0.1ml/100μg 0.2ml/200μg

抗体来源 Rabbit

克隆类型 polyclonal

交叉反应 Human, Mouse, Rat, Rabbit

产品类型一抗

研究领域肿瘤免疫学信号转导 G蛋白偶联受体 G蛋白信号

蛋白分子量 predicted molecular weight: 40kDa

性状 Lyophilized or Liquid

免疫原 KLH conjugated synthetic peptide derived from Human BDKRB1

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 Kinins are important biologically active peptides that mediate cardiovascular homeostasis, inflammation and nociception. Bradykinin, the major effector peptide of the kallikrein-kinin system, is regulated by angiotensin-converting enzyme (ACE), which degrades the peptide. Bradykinin normally exerts its effects through the activation of two seven transmembrane G-protein coupled receptors, named B1 and B2. The B2 receptor is constitutively expressed and preferentially binds full length bradykinin. Deletion of the B2 receptor leads to salt-sensitive hypertension and altered nociception in mice. The B1 receptor binds to derivatives of bradykinin and kallidin, which are produced by carboxypeptidase action to generate the products des-Arg9-bradykinin and des-Arg10-kallidin, respectively. The expression of the B1 receptor is inducible by inflammatory mediators, such as bacterial lipopolysaccharide (LPS) and cytokines. The B1 and B2 receptors represent potential therapeutic targets for treatment of inflammatory disorders and cardiovascular diseases.

缓激肽B1受体抗体Function : This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.

Subunit : Belongs to the G-protein coupled receptor 1 family. Bradykinin receptor subfamily. BDKRB1 sub-subfamily.

Subcellular Location : Cell membrane.

Similarity : Belongs to the G-protein coupled receptor 1 family. Bradykinin receptor subfamily. BDKRB1 sub-subfamily.