蛋白转运抑制剂GBF1抗体elisa实验|0.1ml/100μg 0.2ml/200μg|BJ-3824-上海邦景实业有限公司

蛋白转运抑制剂GBF1抗体elisa实验

参考价：面议

供货周期：

现货

品牌：

GenWay

规格：

0.1ml/100μg 0.2ml/200μg

货号：

BJ-3824

CAS号：

产品详情

蛋白转运抑制剂GBF1抗体英文名称 Anti-Brefeldin A/GBF1

中文名称 蛋白转运抑制剂GBF1抗体

别名 ARF1GEF; BFA resistant GEF 1; BFA-resistant GEF 1; FLJ21263; FLJ21500; GBF1; GBF1_HUMAN; Golgi specific brefeldin A resistance factor 1; Golgi specific Brefeldin A-resistance factor; Golgi-specific brefeldin A-resistance guanine nucleotide exchange; Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1; KIAA0248; MGC134877; MGC134878.

浓度 1mg/1ml

蛋白转运抑制剂GBF1抗体规格 0.2ml/200μg

抗体来源 Rabbit

克隆类型 polyclonal

交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep

产品类型一抗

研究领域细胞生物信号转导

蛋白分子量 predicted molecular weight: 206kDa

性状 Lyophilized or Liquid

免疫原 KLH conjugated synthetic peptide derived from human Brefeldin A

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 Protein trafficking to the membrane requires formation of coated carrier vesicles, such as COPI-coated vesicles from the cis-golgi, a process triggered by membrane binding of the GTP-bound form of ADP-ribosylation factors. Normally, brefeldin A (BFA) blocks this action by inhibiting guanine nucleotide exchange factors (GEFs) for ADP-ribosylation factor. However, GBF1, a member of the sec7-domain family of GEFs, allows cells to maintain normal golgi morphology and grow in the presence of BFA. The gene encoding the human GBF1 protein maps to chromosome 10q24, with the sec7-domain centrally positioned, and a proline-rich 蛋白转运抑制剂GBF1抗体C-terminus. Based on mutatagenesis analysis, this proline rich region appears to interact with p115 in a functionally significant manner.

Function : Promotes guanine-nucleotide exchange on ARF5. Promotes the activation of ARF5 through replacement of GDP with GTP.

Tissue Specificity : Ubiquitous.

Similarity : Contains 1 SEC7 domain.

Database links : UniProtKB/Swiss-Prot: Q92538.2