染色体相关蛋白CAP抗体elisa实验|0.1ml/100μg 0.2ml/200μg|BJ-3844-上海邦景实业有限公司

染色体相关蛋白CAP抗体elisa实验

参考价：面议

供货周期：

现货

品牌：

GenWay

规格：

0.1ml/100μg 0.2ml/200μg

货号：

BJ-3844

CAS号：

产品详情

染色体相关蛋白CAP抗体英文名称 Anti-Brd4/CAP

中文名称 染色体相关蛋白CAP抗体

别名 Brd4; BRD4_HUMAN; bromodomain containing protein 4; Bromodomain-containing protein 4; CAP; chromosome associated protein; HUNK1; Protein HUNK1.

浓度 1mg/1ml

规格 0.2ml/200μg

抗体来源 Rabbit

染色体相关蛋白CAP抗体克隆类型 polyclonal

交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit

产品类型一抗

研究领域肿瘤免疫学表观遗传学

蛋白分子量 predicted molecular weight: 150kDa

性状 Lyophilized or Liquid

免疫原 KLH conjugated synthetic peptide derived from human Brd4/CAP

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 Brd4 belongs to the BET family, a group of structurally related proteins containing two bromodomains. Through these two domains, Brd4 associates with mitotic chromosomes and its expression correlates with cell growth. Expression of Brd4 inhibits cell cycle progression from G(1) to S, due to binding to the largest subunit of replication factor C (RFC) to prevent DNA elongation. Altered Brd4 function correlates with poorly differentiated carcinoma, with aggresive phenotype and a highly lethal outcome.

Subunit : Associated with chromosomes during mitosis. Interacts with bovine papillomavirus type 1 regulatory protein E2.染色体相关蛋白CAP抗体

Subcellular Location : Nucleus.

Tissue Specificity : Ubiquitously expressed.

Similarity : Contains 2 bromo domains.