肿瘤/睾丸抗原2.3抗体elisa实验|0.1ml/100μg 0.2ml/200μg|BJ-3863-上海邦景实业有限公司

肿瘤/睾丸抗原2.3抗体elisa实验

参考价：面议

供货周期：

现货

品牌：

GenWay

规格：

0.1ml/100μg 0.2ml/200μg

货号：

BJ-3863

CAS号：

产品详情

肿瘤/睾丸抗原2.3抗体英文名称 Anti-BAGE3

中文名称 肿瘤/睾丸抗原2.3抗体

别名 B melanoma antigen family member 3; B melanoma antigen 3; BAGE3; BAGE3_HUMAN; Cancer/testis antigen 2.3; Cancer/testis antigen family 2 member 3; CT2.3.

浓度 1mg/1ml

规格 0.2ml/200μg

肿瘤/睾丸抗原2.3抗体抗体来源 Rabbit

克隆类型 polyclonal

交叉反应 Human

产品类型一抗

研究领域肿瘤细胞生物免疫学

蛋白分子量 predicted molecular weight: 10kDa

性状 Lyophilized or Liquid

免疫原 KLH conjugated synthetic peptide derived from human BAGE3

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 Unknown. Candidate gene encoding tumor antigens. Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2 and BAGE 3 (B melanoma antigen 2 and 3, respectively), also known as Cancer/testis antigen 2.2 and 2.3 (respectively), are 109 amino acid secreted proteins that are expressed in 22% of melanomas, lung and bladder carcinomas, and are also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely 肿瘤/睾丸抗原2.3抗体silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis.

Function : Unknown. Candidate gene encoding tumor antigens.

Subcellular Location : Secreted

Tissue Specificity : Not expressed in normal tissues except in testis. Expressed in melanoma, bladder and lung carcinomas.

Similarity : Belongs to the BAGE family.

Database links : UniProtKB/Swiss-Prot: Q86Y29.1