BTB/POZ结构域蛋白1elisa实验|0.1ml/100μg 0.2ml/200μg|BJ-3934-上海邦景实业有限公司

BTB/POZ结构域蛋白1elisa实验

参考价：面议

供货周期：

现货

品牌：

GenWay

规格：

0.1ml/100μg 0.2ml/200μg

货号：

BJ-3934

CAS号：

产品详情

BTB/POZ结构域蛋白1英文名称 Anti-BTBD1

中文名称 BTB/POZ结构域蛋白1（丙型肝炎病毒的NS5A反转录蛋白8）抗体

别名 BTB (POZ) domain containing 1; BTB domain containing 1; BTB/POZ domain containing protein 1; BTBD 1; BTBD1; C15orf1; HCV NS5A transactivated protein 8; Hepatitis C virus NS5A transactivated protein 8; NS5ATP8; BTBD1_HUMAN.

浓度 1mg/1ml

规格 0.2ml/200μg

抗体来源 Rabbit

BTB/POZ结构域蛋白1克隆类型 polyclonal

交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep

产品类型一抗

研究领域细胞生物细胞周期蛋白转录调节因子细菌及病毒细胞分化

蛋白分子量 predicted molecular weight: 53kDa

性状 Lyophilized or Liquid

免疫原 KLH conjugated synthetic peptide derived from human BTBD1

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 BTBD1 contains a proline-rich region and a BTB/POZ domain which are typically involved in protein-protein interactions. The C-terminus of BTBD1 binds topoisomerase I and BTBD1 also interacts with TRIM5 isoform Delta. BTBD1 localizes to cytoplasmic bodies and is essential for myogenic differentiation.

Function : Probable substrate-specific adapter of an E3 ubiquitin-protein ligase BTB/POZ结构域蛋白1complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Subunit : Interacts with topoisomerase 1 and with TRIM5 isoform Delta. Interacts with CUL3.

Subcellular Location : Cytoplasm, P-body. Cytoplasmic bodies.

Tissue Specificity : Ubiquitous; higher levels in heart and skeletal muscle.

Similarity : Contains 1 BTB (POZ) domain.

Database links : UniProtKB/Swiss-Prot: Q9H0C5.1