补体C7抗体elisa实验|0.1ml/100μg 0.2ml/200μg|BJ-3980-上海邦景实业有限公司

补体C7抗体elisa实验

参考价：面议

供货周期：

现货

品牌：

GenWay

规格：

0.1ml/100μg 0.2ml/200μg

货号：

BJ-3980

CAS号：

产品详情

补体C7抗体英文名称 Anti-C7

中文名称 补体C7抗体

别名 C7; CO7_HUMAN; complement component 7; Complement component C7.

浓度 1mg/1ml

规格 0.2ml/200μg

抗体来源 Rabbit

克隆类型 polyclonal

补体C7抗体交叉反应 Human, Mouse, Rat, Pig, Cow, Sheep

产品类型一抗

研究领域细胞生物免疫学

蛋白分子量 predicted molecular weight: 91kDa

性状 Lyophilized or Liquid

免疫原 KLH conjugated synthetic peptide derived from human C7

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍

Function : Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor.

Subunit : Monomer or dimer; as a C5b-7 complex it can also form multimeric rosettes. MAC assembly is initiated by protelytic cleavage of C5 into C5a and C5b. C5b binds sequentially C6, C7, C8 and multiple copies of the pore-forming subunit C9.

Subcellular Location : Secreted.

Post-translational modifications : C7 has 28 disulfide bridges.

O- and C-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans.

DISEASE : Defects in C7 are a cause of complement component 7 deficiency (C7D) [MIM:610102]. A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis.

Similarity : Belongs to the complement C6/C7/C8/C9 family.

C补体C7抗体ontains 1 EGF-like domain.

Contains 1 LDL-receptor class A domain.

Contains 1 MACPF domain.

Contains 2 Sushi (CCP/SCR) domains.

Contains 2 TSP type-1 domains.

Database links : UniProtKB/Swiss-Prot: P10643.2