心房钠尿因子/心钠素/心房利钠肽/ANP抗体|50ul/100ul/200ul|LM2040R-上海联迈生物工程有限公司

心房钠尿因子/心钠素/心房利钠肽/ANP抗体

参考价：¥1580

供货周期：

现货

品牌：

LMAI Bio

规格：

50ul/100ul/200ul

货号：

LM2040R

CAS号：

产品详情

心房钠尿因子/心钠素/心房利钠肽/ANP抗体

英文名称 Atrial natriuretic factor (ANP)

中文名称心房钠尿因子/心钠素/心房利钠肽/ANP抗体

别名 Prepronatriodilatin; ANF_HUMAN; Cardiodilatin; ANF; Atrial natriuretic factor; CDD ANF; CDP; PND; Prepronatriodilatin; Nppa; Natriuretic peptides A; Atrial natriuretic peptide; CDD-ANF; ANP.

研究领域心血管细胞生物信号转导激酶和磷酸酶

抗体来源 Rabbit

克隆类型 Polyclonal

交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig,

产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分子量 3/17kDa

细胞定位分泌型蛋白

性状 Lyophilized or Liquid

浓度 1mg/ml

免疫原 KLH conjugated synthetic peptide derived from human ANP:124-151/153

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed

产品介绍 The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. [provided by RefSeq, Sep 2009].

心钠素（心房利尿钠肽）：心钠素主要是由心房分泌的一种含有28个氨基酸并由二硫键结合的一环形肽分子，具有强大的利钠、利尿、扩血管等作用。使血管舒张，外周阻力降低；使每博输出量变少，心率减慢；肾排水排钠增多；导致体内细胞外液量减少。

心钠素主要来源于心肌纤维，但脑、肾、肺、肾上腺等器官、组织也能表达，但产生及分泌的方式有一定差异。