基质金属蛋白酶2抗体

报价:¥1580
供货周期: 现货
品牌: LMAI Bio
型号: 50ul/100ul/200ul
货号: LM20705R
上海联迈生物工程有限公司
银牌会员7年生产商
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基质金属蛋白酶2抗体

 

英文名称    MMP-2    

中文名称    基质金属蛋白酶2抗体    

别    名    MMP2; MMP 2; 72 kDa gelatinase; 72kD type IV collagenase; CLG 4; CLG 4A; CLG4; CLG4A; Collagenase Type 4 alpha; Collagenase type IV A; Gelatinase A; Gelatinase alpha; Gelatinase neutrophil; Matrix metallopeptidase 2 gelatinase A 72kDa gelatinase 72kDa type IV collagenase; Matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase); Matrix Metalloproteinase 2; Matrix metalloproteinase II; MMP 2; MMP II; MONA; Neutrophil gelatinase; TBE 1.      

研究领域    肿瘤  免疫学  神经生物学  合成与降解      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep,     

产品应用    WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    72kDa    

细胞定位    细胞核 细胞浆 细胞外基质 分泌型蛋白     

性    状    Lyophilized or Liquid    

浓    度    1mg/ml    

免 疫 原    KLH conjugated synthetic peptide derived from human MMP-2:81-150/662     

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

PubMed    PubMed    

产品介绍    This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]    

基质金属蛋白酶(matrix metalloproteinases, MMPs)MMP2是一族依赖锌离子而降解各种细胞外基质的蛋白酶,亦称IV型胶原酶或称明胶酶A,其主要功能为降解IV型胶原,因而它在肿瘤细胞突破基底膜屏障和浸润转移中起重要作用。目前主要用于各种恶性肿瘤(如乳腺癌、胃肠道癌、卵巢癌、膀胱癌等)中的基底膜检测与转移浸润的研究。    

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基质金属蛋白酶2抗体由上海联迈生物工程有限公司为您提供,货号LM20705R,规格:50ul/100ul/200ul,CAS号:,如您想了解更多关于基质金属蛋白酶2抗体价格、基质金属蛋白酶2抗体结构式、批发、用途等信息,欢迎咨询。除供应基质金属蛋白酶2抗体外,还可为您提供G蛋白偶联受体84抗体、G蛋白修补结构域蛋白4抗体等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,LMAI-BIO客户服务电话400-860-5168转4246,售前、售后均可联系。
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