磷酸化肌醇聚磷酸盐磷酸酶样蛋白1抗体

报价:¥1580
供货周期: 现货
品牌: LMAI Bio
型号: 50ul/100ul/200ul
货号: LM3402R
上海联迈生物工程有限公司
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磷酸化肌醇聚磷酸盐磷酸酶样蛋白1抗体

 

英文名称    Phospho-INPPL1 (Ser576)    

中文名称    磷酸化肌醇聚磷酸盐磷酸酶样蛋白1抗体    

别    名    INPPL1(Phospho Ser576); INPPL1(Phospho S576); INPPL1(Phospho-Ser576); 5-trisphosphate 5-phosphatase 2; 51C protein; EC 3.1.3.n1; inositol polyphosphate phosphatase like 1; Inositol polyphosphate phosphatase like protein 1; Inositol polyphosphate phosphatase-like protein 1; INPPL-1; INPPL1; Phosphatidylinositol 3; Phosphatidylinositol 3,4,5 trisphosphate 5 phosphatase 2; Protein 51C; SH2 domain containing inositol 5' phosphatase 2; SH2 domain-containing inositol 5''-phosphatase 2; SH2 domain-containing inositol phosphatase 2; SHIP-2; SHIP2; SHIP2_HUMAN.      

产品类型    磷酸化抗体     

研究领域    肿瘤  心血管  免疫学  神经生物学  信号转导  生长因子和激素  激酶和磷酸酶  细胞骨架  新陈代谢  细胞外基质      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,     

产品应用    WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    139kDa    

细胞定位    细胞浆 细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/ml    

免 疫 原    KLH conjugated Synthesised phosphopeptide derived from human SHIP1 around the phosphorylation site of Ser576:QN(p-Y)LD     

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

PubMed    PubMed    

产品介绍    The steady state of protein tyrosyl phosphorylation in cells is regulated by the opposing action of tyrosine kinases and protein tyrosine phosphatases (PTPs). Several groups have independently identified a non transmembrane PTP, designated SHPTP1 (also known as PTP1C, HCP and SHP), which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N terminal to the PTP domain. A second and much more widely expressed PTP with SH2 domains, SHPTP2 (also designated PTP1D and Syp), has been identified. SHP2 is a protein tyrosine phosphatase that is widely expressed and plays a regulatory role in various cell signaling events that are important for many cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration.    

SHP2(SH-PTP2)参与多种细胞内信号传导 如MAP kinase、 PI3k等途径,SHP2也是许多其他原癌基因信号通路的重要组成部分,在细胞的增殖及分化等过程扮演重要的角色.

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磷酸化肌醇聚磷酸盐磷酸酶样蛋白1抗体由上海联迈生物工程有限公司为您提供,货号LM3402R,规格:50ul/100ul/200ul,CAS号:,如您想了解更多关于磷酸化肌醇聚磷酸盐磷酸酶样蛋白1抗体价格、磷酸化肌醇聚磷酸盐磷酸酶样蛋白1抗体结构式、批发、用途等信息,欢迎咨询。除供应磷酸化肌醇聚磷酸盐磷酸酶样蛋白1抗体外,还可为您提供糖原合酶激酶-3β抗体、丝裂原活化蛋白激酶1/ERK 1/2抗体等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,LMAI-BIO客户服务电话400-860-5168转4246,售前、售后均可联系。
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