供货周期: | 现货 |
品牌: | LMAI Bio |
规格: | 50ul/100ul/200ul |
货号: | LM7944R |
CAS号: |
泛素蛋白抗体
英文名称 Ubiquitin
中文名称 泛素蛋白抗体
别 名 FLJ25987; MGC8385; RPS27A; RPS 27A; UBA52; UBA 52; UBA80; UBA 80; UBB; UBC; UB; UBCEP1; UBCEP2; UBCEP 1; UBCEP 2; UBCEP-1; UBCEP-2; Ubiquitin; ubiquitin B; UBC_HUMAN; UBB_HUMAN; RS27A_HUMAN; HMG20; Ubiquitin carboxyl extension protein 80; Ubiquitin; Polyubiquitin-C; Polyubiquitin-B.
研究领域 肿瘤 细胞生物 免疫学 神经生物学 细胞凋亡 泛素
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Chicken, Cow, Sheep,
产品应用 WB=1:500-2000 ELISA=1:500-1000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 8.5kDa
细胞定位 细胞核 细胞浆
性 状 Lyophilized or Liquid
浓 度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Ubiquitin:63-74/76
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
泛素及类泛素蛋白(Ubls) 存在在多种细胞中,有多种细胞调控的功能,如细胞增殖、凋亡、细胞周期及DNA修复等。但泛素途径的异常会导致人类疾病的产生,包括多种形式的肿瘤的发生,神经退变等都与泛素有关。
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