嗜酸性粒细胞阳离子蛋白抗体|50ul/100ul/200ul|LM8615R-上海联迈生物工程有限公司

嗜酸性粒细胞阳离子蛋白抗体

参考价：¥1580

供货周期：

现货

品牌：

LMAI Bio

规格：

50ul/100ul/200ul

货号：

LM8615R

CAS号：

产品详情

嗜酸性粒细胞阳离子蛋白抗体

英文名称 Ribonuclease 3/ECP

中文名称嗜酸性粒细胞阳离子蛋白抗体

别名 eosinophil cationic protein; EAR; Ear11; Ear4; EAR5; ECP; LOC192264; MGC143624; mR3; mR5; R1; R14; R15; R17; R5; R7; Ribonuclease 3; Rnase17; Rnase2; RNASE3; RNS3; ECP_HUMAN.

研究领域细胞生物免疫学通道蛋白

抗体来源 Rabbit

克隆类型 Polyclonal

交叉反应 Human,

产品应用 ELISA=1:500-1000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分子量 16kDa

细胞定位细胞浆

性状 Lyophilized or Liquid

浓度 1mg/ml

免疫原 KLH conjugated synthetic peptide derived from human Ribonuclease 3:45-160/160

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed

产品介绍 ECP is a 160 amino acid potent cytotoxic secretory protein that belongs to the pancreatic ribonuclease family. ECP localizes to the granule matrix of the eosinophil and is involved in the immune response system. ECP is a cytotoxin, neurotoxin and helminthotoxin that is secreted by activated human eosinophils. ECP exhibits anti-parasitic, antibacterial and ribonucleolytic activities. It has been suggested that ECP induces the neurotoxic effect known as the Gordon phenomenon, a syndrome manifested by ataxia, muscular rigidity, paralysis, and tremor that may lead to death. ECP is considered a marker of eosinophilic inflammation and high levels have been found in cases of active asthma and other allergic diseases