环指蛋白123抗体

报价:¥1580
供货周期: 现货
品牌: LMAI Bio
型号: 50ul/100ul/200ul
货号: LM9249R
上海联迈生物工程有限公司
银牌会员7年生产商
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环指蛋白123抗体

 

英文名称    RNF123    

中文名称    环指蛋白123抗体    

别    名    E3 ubiquitin protein ligase RNF123; Kip1 ubiquitination promoting complex protein 1; KPC 1; KPC1; Ring finger protein 123; RNF 123; Ubiquitin ligase;       

研究领域    细胞生物  免疫学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig,     

产品应用    WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    149kDa    

细胞定位    细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/ml    

免 疫 原    KLH conjugated synthetic peptide derived from human RNF123:1-100/1314     

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

PubMed    PubMed    

产品介绍    The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in protein-protein interactions and protein-DNA interactions. RNF123 (RING finger protein 123), also known as KPC1 (Kip1 (p27) ubiquitination-promoting complex protein 1) or FP1477, contains one RING-type zinc finger domain and one SPRY domain. Localizing to the cytoplasm, RNF123 functions as the catalytic component of the KPC complex that acts as an E3 ubiquitin-protein ligase. Specifically, RNF123 is essential for the ubiquitination and subsequent degradation of p27 during the cell cycle G1 phase. Via its N-terminus, RNF123 is known to interact with GBDR1 (another component of the KPC) and p27 (a cyclin-dependent kinase inhibitor). Due to alternative splicing events, two isoforms exist for RNF123.    


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环指蛋白123抗体由上海联迈生物工程有限公司为您提供,货号LM9249R,规格:50ul/100ul/200ul,CAS号:,如您想了解更多关于环指蛋白123抗体价格、环指蛋白123抗体结构式、批发、用途等信息,欢迎咨询。除供应环指蛋白123抗体外,还可为您提供溶质载体家族蛋白26成员3抗体、溶质载体家族蛋白25成员38抗体等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,LMAI-BIO客户服务电话400-860-5168转4246,售前、售后均可联系。
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