磷酸化心肌肌钙蛋白抗体

磷酸化心肌肌钙蛋白抗体

英文名称    phospho-cardiac Troponin I (Thr143)    

中文名称    磷酸化心肌肌钙蛋白抗体    

别    名    cardiac Troponin I (phospho Thr143); p-cardiac Troponin I (Thr143); cardiac Troponin I (phospho T143); p-cardiac Troponin I (T143); Cardiac troponin I; Cardiomyopathy, familial hypertrophic, 7, included; CMD1FF; CMD2A; CMH7; cTnI; Familial hypertrophic cardiomyopathy 7; MGC116817; RCM1; p-Tn1; p-Tni; TNN I3; p-TNNC 1; p-TNNC1; p-TNNI3; p-Troponin I cardiac; Troponin I cardiac muscle; Troponin I cardiac muscle isoform; Troponin I type 3 cardiac; troponin I, cardiac 3; TroponinI; TNNI3_HUMAN.      

产品类型    磷酸化抗体     

研究领域    心血管  信号转导  细胞骨架      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,     

产品应用    ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    24 kDa    

细胞定位    细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/ml    

免 疫 原    KLH conjugated synthesised phosphopeptide derived from human cardiac Troponin I around the phosphorylation site of Thr143:RP(p-T)LR     

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

PubMed    PubMed    

产品介绍    Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq].    

心肌肌钙蛋白（Cardiac Troponin CTn1）是心肌收缩的调节蛋白，存在于心肌收缩蛋白的细肌丝上。肌钙蛋白的作用之一是把原肌凝蛋白（Tropomyosin.Tm）附着于肌动蛋白（Action.A）上、 主要用于心肌功能方面的研究。