供货周期: | 现货 |
品牌: | LMAI Bio |
规格: | 50ul/100ul/200ul |
货号: | LM0933M |
CAS号: |
GLP-1单克隆抗体
英文名称 GLP-1(1G9)
中文名称 GLP-1单克隆抗体
别 名 GCG; GLP 1; glucagon; Glucagon like peptide 1; GRPP; GLP-1(7-36); GLP-1(7-37); Oxyntomodulin; OXM; OXY; GLUC_HUMAN.
研究领域 肿瘤 心血管 免疫学 神经生物学 信号转导 生长因子和激素 糖尿病 内分泌病 新陈代谢
抗体来源 Mouse
克隆类型 Monoclonal
克 隆 号 1G9
交叉反应 Human, Mouse, Rat,
产品应用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 21kDa
细胞定位 分泌型蛋白
性 状 Lyophilized or Liquid
浓 度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GLP-1:1-31/31
亚 型 IgG
纯化方法 affinity purified by Protein G
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. GLP-1 is a potent stimulator of glucose-dependent insulin release. Play important roles on gastric motility and the suppression of plasma glucagon levels. May be involved in thesuppression of satiety and stimulation of glucose disposal in peripheral tissues, independent of the actions of insulin. Have growth-promoting activities on intestinal epithelium. May also regulate the hypothalamic pituitary axis (HPA) via effects on LH, TSH, CRH, oxytocin, and vasopressin. Belongs to the glucagon family.
胰高血糖素(Glucagon)在糖代谢和体内平衡中起重要作用,通过释放糖原和糖酵解调节血糖。作为反调节激素的胰岛素,当血糖升高时,胰岛素可诱导低血糖。
胰高血糖素样肽-1(Glucagon-like peptide-1, GLP-1)是一个具有强的刺激糖依赖的胰岛素释放的肽,在胃运动性和抑制血糖水平上起重要作用。还可能参与外周组织糖的控制,不依赖胰岛素的作用。具有促进肠上皮生长等作用。GLP-1属于胰高血糖素家族成员。
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