糖皮质激素调节激酶1单克隆抗体

报价:¥1580
供货周期: 现货
品牌: LMAI Bio
型号: 50ul/100ul/200ul
货号: LM33275M
上海联迈生物工程有限公司
银牌会员7年生产商
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糖皮质激素调节激酶1单克隆抗体

 

英文名称    SGK1    

中文名称    糖皮质激素调节激酶1单克隆抗体    

别    名    Serum/glucocorticoid regulated kinase 1; SGK 1; SGK-1; Serine/threonine protein kinase SGK; Serine/threonine protein kinase Sgk1; Serum and glucocorticoid regulated kinase; Serum/glucocorticoid regulated kinase; SGK 1; SGK; SGK1_HUMAN.      

研究领域    肿瘤  细胞生物  免疫学  信号转导  生长因子和激素  转录调节因子  激酶和磷酸酶      

抗体来源    Mouse    

克隆类型    Monoclonal    

克 隆 号    5E11    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,     

产品应用    IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    49kDa    

细胞定位    细胞核 细胞浆 细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/ml    

免 疫 原    KLH conjugated synthetic peptide derived from human SGK1:     

亚    型    IgG    

纯化方法    affinity purified by Protein G    

储 存 液    0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

PubMed    PubMed    

产品介绍    SGK1 is a protein kinase that plays an important role in cellular stress response. SGK1 activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. Sustained high levels of SGK1 and activity may contribute to conditions such as hypertension and diabetic nephropathy. This protein also mediates cell survival signals, as it has been shown to phosphorylate and negatively regulate the pro apoptotic FOXO3A protein. Ser 422 is a critical site on the protein and may be involved in its activation.    



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糖皮质激素调节激酶1单克隆抗体由上海联迈生物工程有限公司为您提供,货号LM33275M,规格:50ul/100ul/200ul,CAS号:,如您想了解更多关于糖皮质激素调节激酶1单克隆抗体价格、糖皮质激素调节激酶1单克隆抗体结构式、批发、用途等信息,欢迎咨询。除供应糖皮质激素调节激酶1单克隆抗体外,还可为您提供5号染色体开放阅读框42抗体、5号染色体开放阅读框34抗体等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,LMAI-BIO客户服务电话400-860-5168转4246,售前、售后均可联系。
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