| 供货周期： | 一周 |
| 品牌： | 爱必信 |
| 规格： | 99% |
| 货号： | abs812950 |
| CAS号： | 10338-51-9 |
| 公告提醒：爱必信所有产品和服务仅用于科学研究，不用于临床应用及其他用途提供产品和服务（也不为任何个人提供产品和服务）!
抑制剂描述： 产品名称：Salidroside 产品别名：见爱必信官网 英文别名：Salidroside 靶点：Phenols CAS：10338-51-9 纯度：99% 外观：见爱必信官网 保存方法：-20℃ 描述： Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola crenulata. 溶解性：Ethanol : 4 mg/mL (13.32 mM) 体外研究： Salidroside inhibits the growth of various human cancer cell lines in concentration- and time-dependent manners, and the sensitivity to salidroside is different in those cancer cell lines. Salidroside could cause G1-phase or G2-phase arrest in different cancer cell lines, meanwhile, salidroside resultes in a decrease of CDK4, cyclin D1, cyclin B1 and Cdc2, and upregulates the levels of p27(Kip1) and p21(Cip1). Salidroside also alleviates cell viability loss and apoptotic cell death induced by H(2)O(2) stimulation in cultured NGF-differentiated PC12 cells by activating ERK1/2 pathway and inhibiting caspase-3 activation. Salidroside activates the PI3K/Akt pathway resulting in protective effects against MPP(+)-induced apoptosis in PC12 cells, which may be used in the treatment of Parkinson's disease (PD). 体内研究：Salidroside (20, 50 and 100 mg/kg) protects liver tissue from the oxidative stress elicited by D-galactosamine and lipopolysaccharide.
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