Polydatin

Polydatin

参考价:¥683
供货周期: 一周
品牌: 爱必信
规格: ≥98%
货号: abs814804
CAS号: 65914-17-2
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抑制剂描述:

产品名称:Polydatin

产品别名:见爱必信官网

英文别名:Polydatin

靶点:Phenols

CAS:65914-17-2

纯度:≥98%

外观:见爱必信官网

保存方法:Store at -20° C

描述:

Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline structure. While it is isolated from the bark of Picea sitchensis or Polygonum cuspidatum, Polydatin may be detected in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products and many daily diets. Polydatin possesses anti-inflammatory, immunoregulatory, anti-oxidative and anti-tumor activities. It is shown to mediate a cytotoxic action on colorectal cancer cells by inducing cell arrest and apoptosis.

溶解性:DMSO :78 mg/mL (199.81 mM)

体外研究:

Polydatin, known as a PLA2 inhibitor, reduces Phospholipase A2 (PLA2) activity and sPLA2-IIA mRNA expression and mitigates LPS-induced lung injury by increasing increased Clara cell secretory protein (CCSP) expression.

体内研究:Pretreatment with Polydatin (15, 45, and 100 mg/kg) dose-dependently reduces sepsis-induced mortality and lung injury in cecal ligation and puncture (CLP-)induced sepsis mice through inhibiting CLP-induced serum tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) production, lung cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase isoform (iNOS) protein expressions and NF-kappaB activation. LD50: Mice 1g/kg (i.p.)

产品信息订购:

  产品货号   产品名称   规格 价格 大包装及货期
  abs814804   Polydatin   50mg   683.00   立即咨询
  abs814804   Polydatin   200mg   1365.00   立即咨询

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