HS-1371|98%|abs821641-爱必信(上海)生物科技有限公司

HS-1371

参考价：¥1512

供货周期：

一周

品牌：

爱必信

规格：

98%

货号：

abs821641

CAS号：

2158197-70-5

产品详情

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抑制剂描述：

产品名称：HS-1371

产品别名：见爱必信官网

英文别名：HS-1371

靶点：RIP Kinase

CAS：2158197-70-5

纯度：98%

外观：见爱必信官网

保存方法：store at -20℃ for one year（Powder）

描述：HS-1371 is a potent and ATP-competitive receptor-interacting protein kinase 3 (RIP3) inhibitor with an IC50 of 20.8?nM.

溶解性：

体外研究：

HS-1371 directly binds to RIP3 in an ATP-competitive and time-independent manner. HS-1371 has an inhibitory effect on RIP3 kinase activity in various cell lines.HS-1371 (0.1, 1, 5, 10, 20 μM, 9 h) can block RIP3 S227 phosphorylation.HS-1371 (0.1, 1, 5, 10 μM, 24 h) rescues cells from RIP3-dependent necroptotic cell death but not apoptotic cell death.Western Blot AnalysisCell Line:HT-29 cells Concentration:0.1, 1, 5, 10, 20 μMIncubation Time:9 hoursResult:Showed an inhibitory effect on S227 auto-phosphorylation of RIP3.

体内研究：HS-1371 directly binds to RIP3 in an ATP-competitive and time-independent manner. HS-1371 has an inhibitory effect on RIP3 kinase activity in various cell lines.HS-1371 (0.1, 1, 5, 10, 20 μM, 9 h) can block RIP3 S227 phosphorylation.HS-1371 (0.1, 1, 5, 10 μM, 24 h) rescues cells from RIP3-dependent necroptotic cell death but not apoptotic cell death.Western Blot AnalysisCell Line:HT-29 cells Concentration:0.1, 1, 5, 10, 20 μMIncubation Time:9 hoursResult:Showed an inhibitory effect on S227 auto-phosphorylation of RIP3.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs821641	HS-1371	5mg	1512.00	立即咨询
abs821641	HS-1371	25mg	4613.00	立即咨询

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