7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide|≥97%|abs42014845-爱必信(上海)生物科技有限公司

7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide

参考价：¥1470

供货周期：

一周

品牌：

爱必信

规格：

≥97%

货号：

abs42014845

CAS号：

138977-28-3

产品详情

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试剂描述：

产品名称：Capsazepine

产品别名：7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide

CAS号：138977-28-3

英文别名：Capsazepine

分子量：376.90

分子式：C₁₉H₂₁ClN₂O₂S

纯度：≥97%

外观：见爱必信官网

保存方法：Store at -20° C

描述：Capsazepine is a competitive antagonist of the VR1 (TRPV1, also transient receptor potential vanilloid type 1), antagonizing the effects produced by Capsaicin at this receptor . The VR1 (TRPV1 receptor) is a non-selective ligand-gated cation channel that responds to noxious heat, protons, and Capsaicin, producing nociception signals. Capsazepine also activates ENaCδ (amiloride-sensitive epithelial Na⁺ channel). Capsazepine is shown to inhibit the development of mechanical hyperalgesia induced by intraplanar capsaicin injection. Capsazepine is described to block Resiniferatoxin - and Capsaicin-induced contractions of guinea pig treacheal smooth muscle. Studies investigating the function of the VR1 (TRPV1 receptor) have employed Capsazepine as a tool for perturbing systemic neuronal response to Capsaicin.

应用：An antagonist of TRPV1 and activator of ENaC

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs42014845	Capsazepine	5mg	1470.00	立即咨询
abs42014845	Capsazepine	25mg	3894.00	立即咨询
abs42014845	Capsazepine	10mg	1800.00	立即咨询

产品更多信息请进入爱必信网站咨询

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