供货周期: | 一周 |
品牌: | 爱必信 |
规格: | ≥97% |
货号: | abs42012566 |
CAS号: | 85547-22-4 |
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试剂描述: 产品名称:Aaptamine 产品别名:8,9-Dimethoxy-1H-benzo[de][1,6]naphtyridine CAS号:85547-22-4 英文别名:Aaptamine 分子量:228.25 分子式:C13H12N2O2 纯度:≥97% 外观:见爱必信官网 保存方法:Store at -20° C 描述: Aaptamine is a spongean alkaloid that can activate the p21 promoter in the absence of p53 and can function as a proteasome inhibitor. The compound is a competitive antagonist of AR (α-adrenoreceptors) in vascular smooth muscle. Aaptamine can be converted to isoaaptamine, 9-demethylaaptamine, and 4-methylaaptamine, with some of the aaptamine derivatives, such as 9-demethylaaptamine, showing antimicrobial activities. Research suggests that aaptamine can inhibit cancer cell growth and that its cytotoxicity may be due to its ability to intercalate DNA. Aaptamine is an inhibitor of CTRL. 应用:A spongean alkaloid that can activate the p21 promoter in the absence of p53
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