供货周期: | 一周 |
品牌: | 爱必信 |
规格: | ≥95% |
货号: | abs42016102 |
CAS号: | 22144-77-0 |
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试剂描述: 产品名称:Cytochalasin D 产品别名:Zygosporin A CAS号:22144-77-0 英文别名:Cytochalasin D 分子量:507.62 分子式:C30H37NO6 纯度:≥95% 外观:见爱必信官网 保存方法:Store at -20° C 描述: Cytochalasin D is used in actin polymerization studies and cytological research. Cytochalasins are fungal toxins characterized by a highly substituted hydrogenated isoindole ring to which is fused a macrocyclic ring. They are believed to bind to the barbed end of actin filaments resulting in inhibition of both the association and dissociation of subunits. Cytochalasin D is about 10-fold more effective than cytochalasin B and does not inhibit monosaccharide transport across cell membranes. Treatment of cells with cytochalasin D results in rapid tyrosine phosphorylation of fish (SH3PXD2A), along with activation of Src. Cytochalasin D has been shown to increase intracellular Ca2+ levels and to activate p53-dependent pathways, causing arrest of the cell cycle. It may also act as an inhibitor of DNA synthesis, thyroid secretion, and growth hormone release. 应用:A cell cycle arresting compound used in actin polymerization studies and cytological research
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