供货周期: | 一周 |
品牌: | 爱必信 |
规格: | ≥98% |
货号: | abs9107 |
CAS号: | 16561-29-8 |
公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)!
试剂描述: 产品名称:PMA 产品别名:佛波醇12-十四酸酯13-乙酸酯(佛波酯);12-十四酸酯13-乙酸佛波醇酯;Phorbol-12-Myristate-13-Acetate CAS号:16561-29-8 英文别名:PMA 分子量:616.83 分子式:C36H56O8 纯度:≥98% 外观:见爱必信官网 保存方法:Store at -20° C,3 years. 描述: PMA (Phorbol-12-Myristate-13-Acetate) is a diester of phorbol and is a tumor promoting compound extracted from croton oil. It is a reversible, highly potent protein kinase C (PKC) activator in vitro and in vivo at nM concentrations. PMA’s effects on PKC are attributed to its similarity to diacylgylerol, a natural activator of PKC. PMA activates Ca2+-ATPase and potentiates forskolin-induced cAMP formation. It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells. 应用:A reversible and highly potent protein kinase C (PKC) activator
产品信息订购:
|
相关产品
详细地址
关注
拨打电话
留言咨询