Recombinant Human Sialic Acid Binding Ig-Like Lectin 3/Siglec-3/CD33 (C-Fc-6His), 人蛋白Sialic Acid Binding Ig-Like Lectin 3/Siglec-3/CD33 (C-Fc-6His)

Recombinant Human Sialic Acid Binding Ig-Like Lectin 3/Siglec-3/CD33 (C-Fc-6His), 人蛋白Sialic Acid Binding Ig-Like Lectin 3/Siglec-3/CD33 (C-Fc-6His)

参考价:¥672
供货周期: 一周
品牌: 爱必信
规格: 10ug
货号: abs04014
CAS号:
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产品描述:

产品名称:Recombinant Human Sialic Acid Binding Ig-Like Lectin 3/Siglec-3/CD33 (C-Fc-6His)

描述: Recombinant Human Sialic Acid Binding Ig-like Lectin 3 is produced by our Mammalian expression system and the target gene encoding Asp18-His259 is expressed with a Fc, 6His tag at the C-terminus.

氨基酸序列: DPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISGDSPVATNKLDQEV QEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKI LIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTC QVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHTSDIEGRMDEPKSCDKTH TCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKT KPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVS?NKALPAPIEKTISKAKGQPREPQVYTL PPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSR WQQGNVFSCSVMHEALHNHYTQKSLSLSPGKVDHHHHHH

背景说明: CD33 is a type I Lectin belonging to the Ig superfamily. CD33 contains an N terminal Ig like V type domain, which mediates sialic acid binding, followed by one Ig like C2 type domain, a transmembrane region and a cytoplasmic tail containing two conserved immunoreceptor tyrosine based inhibition motifs (ITIMs). Eleven human Siglecs have been characterized. Siglecs 5 to 11 share a high degree of sequence similarity with CD33/Siglec3 both in their extracellular and intracellular regions. They are collectively referred to as CD33 related Siglecs. CD33 related Siglecs have differential expression pattern within the hematopoietic system. They are involved in the regulation of cellular activation within the immune system. Siglec 3 expression is restricted to cells of myelomonocytic lineage. Siglec3 recruits SHP1 and SHP2 to its ITIMs upon phosphorylation.

别名: Myeloid Cell Surface Antigen CD33, Sialic Acid-Binding Ig-Like Lectin 3, Siglec-3, gp67, CD33, SIGLEC3

Accession: P20138

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Human Cells

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

形态: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 2mM EDTA, pH 7.2.

储存/保存方法: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

产品信息订购:

  产品货号   产品名称   规格 价格 大包装及货期
  abs04014   Recombinant Human Sialic Acid Binding Ig-Like Lectin 3/Siglec-3/CD33 (C-Fc-6His)   10ug   672.00   立即咨询
  abs04014   Recombinant Human Sialic Acid Binding Ig-Like Lectin 3/Siglec-3/CD33 (C-Fc-6His)   50ug   1848.00   立即咨询
  abs04014   Recombinant Human Sialic Acid Binding Ig-Like Lectin 3/Siglec-3/CD33 (C-Fc-6His)   500ug   12936.00   立即咨询
  abs04014   Recombinant Human Sialic Acid Binding Ig-Like Lectin 3/Siglec-3/CD33 (C-Fc-6His)   1mg   17600.00   立即咨询

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