Recombinant Human Fibroblast Growth Factor 21/FGF-21 (N-6His), 人蛋白Fibroblast Growth Factor 21/FGF-21 (N-6His)|10ug|abs04192-爱必信(上海)生物科技有限公司

Recombinant Human Fibroblast Growth Factor 21/FGF-21 (N-6His), 人蛋白Fibroblast Growth Factor 21/FGF-21 (N-6His)

参考价：¥672

供货周期：

一周

品牌：

爱必信

规格：

10ug

货号：

abs04192

CAS号：

产品详情

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产品描述：

产品名称：Recombinant Human Fibroblast Growth Factor 21/FGF-21 (N-6His)

描述: Recombinant Human Fibroblast Growth Factor 21 is produced by our E.coli expression system and the target gene encoding His29-Ser209 is expressed with a 6His tag at the N-terminus.

氨基酸序列: MGSSHHHHHHSSGLVPRGSHMHPIPDSSPLLQFGGQVRQRYLYTDDAQQTEAHLEIREDGTVGGA ADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPEACSFRELLLEDGYNVYQS EAHGLPLHLPGNKSPHRDPAPRGPARFLPLPGLPPAPPEPPGILAPQPPDVGSSDPLSMVGPSQG RSPSYAS

背景说明: Fibroblast Growth Factor 21 (FGF21) is a growth factor that belongs to the FGF family. FGF family proteins play a central role during prenatal development and postnatal growth and regeneration of mamy tissues, by promoting cellular proliferation and differentiation. FGF21 is a potent activator of glucose uptake on adipocytes, protects animal from diet-induced obesity when overexpression in transgenic mice, and lower blood glucose and triglyceride levels when therapeutically adiministered to diabetic redents. FGF21 is produced by hepatocytes in reponse to free fatty acid stimulation of a PPARa/RXR dimeric complex. This situation occurs clinically during starvation, or following the ingestionof a highly-fat/low-carbohydrate diet.Upon FGF21 secretion, white adipose tissue is induced to release free fatty acids from triglyceride stores. Once free fatty acid reach hepatocytes, they are oxidized and reduced to acetyl-CoA. The acetyl-CoA is recombined into 4-carbon ketone bodies, release, and transported to peripheral tissue for TCA processing and energy generation.

别名: Fibroblast Growth Factor 21, FGF-21, FGF21

Accession: Q9NSA1

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Escherichia coli.

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

形态: Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 100mM NaCl, 2mM EDTA, pH9.0 .

储存/保存方法: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs04192	Recombinant Human Fibroblast Growth Factor 21/FGF-21 (N-6His)	10ug	672.00	立即咨询
abs04192	Recombinant Human Fibroblast Growth Factor 21/FGF-21 (N-6His)	50ug	1848.00	立即咨询
abs04192	Recombinant Human Fibroblast Growth Factor 21/FGF-21 (N-6His)	500ug	12936.00	立即咨询
abs04192	Recombinant Human Fibroblast Growth Factor 21/FGF-21 (N-6His)	1mg	17600.00	立即咨询

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